Volume 21 (2024)
Volume 20 (2023)
Volume 19 (2022)
Volume 18 (2021)
Volume 17 (2020)
Volume 16 (2019)
Volume 15 (2018)
Volume 14 (2017)
Volume 13 (2016)
Volume 12 (2015)
Volume 11 (2014)
Volume 10 (2013)
Volume 9 (2012)
Volume 8 (2011)
Volume 7 (2010)
Volume 6 (2009)
Volume 5 (2008)
Volume 4 (2007)
Volume 3 (2006)
Volume 2 (2005)
Volume 1 (2004)
Evaluation of Innate Lymphoid Cells (ILCs) Population in the Mouse Model of Colorectal Cancer

Seyed Mohammad Javadzadeh; Mohsen Keykhosravi; Mohsen Tehrani; Hossein Asgarian-Omran; Mohsen Rashidi; Hadi Hossein-Nattaj; Laleh Vahedi-Larijani; Abolghasem Ajami

Volume 19, Issue 4 , December 2022, , Pages 339-348

https://doi.org/10.22034/iji.2022.92467.2152

Abstract
  Background: Innate Lymphoid Cells (ILCs) promote tissue homeostasis, contribute to the immune defense mechanisms, and play important roles in the initiation of immune responses and chronic inflammation. Objective: To understand the roles of innate lymphoid cells in the pathophysiology of colorectal ...  Read More

Treatment by PI3K/mTOR Inhibitor BEZ235 Combined with TLR-7/8 Agonist Interfere with Immune Evasion Mechanisms of WEHI-3 Mouse Leukemia Cells

Saeid Taghiloo; Abolghasem Ajami; Reza Alizadeh-Navaei; Ehsan Zaboli; Hossein Asgarian-Omran

Volume 19, Issue 1 , March 2022, , Pages 58-70

https://doi.org/10.22034/iji.2022.92576.2155

Abstract
  Background: Several PI3K/Akt/mTOR pathway inhibitors and TLR agonists induce tumor cell death. However, the mechanisms of these therapeutic approaches in acute myeloid leukemia (AML) cells are still unknown. Objectives: To investigate the effects of BEZ235, as a dual inhibitor of PI3K and mTOR pathways, ...  Read More

Cytokine profiling in Iranian patients with COVID-19; association with clinical severity

Saeid Taghiloo; Mohsen Soltanshahi; Masoud Aliyali; Siavash Abedi; Hossein Mehravaran; Abolghasem Ajami; Hossein Asgarian-Omran

Volume 18, Issue 1 , March 2021, , Pages 54-64

https://doi.org/10.22034/iji.2021.87630.1810

Abstract
  Background: SARS-CoV-2, the virus that causes coronavirus disease 2019 (COVID-19), is recognized for the first time in Wuhan, China. The cytokine storm is a known factor causing major clinical symptoms leading to death in COVID-19 patients. Objective: To investigate and compare the serum levels of ...  Read More