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Hemin Induces the Activation of NLRP3 Inflammasome in N9 Microglial Cells

Yan Tan; Si-Wei Tan; Bo-Ya Fan; Lei Li; Yuan-Guo Zhou

Volume 15, Issue 2 , June 2018, , Pages 122-132

https://doi.org/10.22034/iji.2018.39376

Abstract
  Background: Hemin is an important sterile component that induces a neuroinflammatory response after intracerebral hemorrhage, in which NLRP3 inflammasome activation has also proved to be involved. Although microglial activation acts as a key contributor in the neuroinflammatory response, the relationship ...  Read More