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1. Hepcidin Induces M1 Macrophage Polarization in Monocytes or THP-1 Derived Macrophages

Enna Liu; Zheng Li; Yan Zhang; Kuisheng Chen

Volume 16, Issue 3 , Summer 2019, , Pages 190-199

Abstract
  Background: Macrophage polarization plays a critical role in determining the inflammatory states. Hepcidin is a key negative regulator of iron homeostasis and functions. Although hepcidin has been shown to affect ferroportin expression in macrophages, whether it affects macrophage polarization is still ...  Read More