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MiR-143 Induces Expression of AIM2 and ASC in Jurkat Cell Line

Mohammad Momeni; Mohammad Reza Mirzaei; Nahid Zainodini; Gholamhossein Hassanshahi; Mohammad Kazemi Arababadi

Volume 10, Issue 2 , June 2013, , Pages 103-109

Abstract
  Background: Absent in Melanoma 2 (AIM2) is an intracellular microbial dsDNA sensor which plays an important role in production of proinflammatory cytokines through Apoptosis associated Speck-like protein containing a Caspase activation and recruitment domain (ASC) and Caspase-1. Micro-RNAs (miRNAs) play ...  Read More