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Effect of Ibuprofen on IL-1β, TNF-α and PGE2 Levels in Periapical Exudates: A Double Blinded Clinical Trial

Shahriar Shahriari; Aliasghar Rezaei; Seyed Mohsen Jalazadeh; Khosro Mani; Alireza Zamani

Volume 8, Issue 3 , September 2011, , Pages 176-182

Abstract
  Background: Bone resorption is one of the main features of inflammatory periapical lesions and is mainly mediated by interleukin-1 beta (IL-1β), tumor necrosis factoralpha (TNF-α) and prostaglandin-E2 (PGE2). Recent investigations of these lesions revealed that pharmacological modulation may ...  Read More