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Natural Killer Cell Cytotoxicity Against SKOV3 after HLA-G Downregulation by shRNA

Nazanin Nazari; Shirin Farjadian

Volume 13, Issue 3 , September 2016, , Pages 178-185

Abstract
  Background: HLA-G is a nonclassical HLA class I molecule which, when elevated in tumor cells, is one of the main factors involved in tumor evasion of immune responses including NK and T cells. Objective: To evaluate the effect of HLA-G downregulation on NK cell cytotoxicity in tumor cell lines. Methods: ...  Read More