@article { author = {Ling, Luoya and Wang, Youqing and Ding, Ye and Zheng, Lin and Qi, Xiaohua and Jin, Mingjuan and Chen, Kun and Xie, Shuyun}, title = {Disseminated Bacillus Calmette-Guérin Disease after BCG Vaccination: A Case Report from China}, journal = {Iranian Journal of Immunology}, volume = {12}, number = {1}, pages = {70-73}, year = {2015}, publisher = {Shiraz Institute for Cancer Research}, issn = {1735-1383}, eissn = {1735-367X}, doi = {}, abstract = {Background: Bacillus Calmette-Guérin (BCG) vaccination is recommended for newborn infants worldwide to prevent tuberculosis. However, complications do occur inevitably in a very low rate, among which the most serious is disseminated disease. The disseminated bacillus Calmette–Guérin disease is a rare disease with high fatality, and can be seen among persons with an underlying immunodeficiency. Case presentation: We report a 4-month-old male infant presenting with recurrent fever, an isolated left axillary massand swelling at the site of BCG inoculation. The cellular immune function analysis showed that the value of CD4/CD8 was 0.994, indicating the existence of immunodeficiency.The results of blood culture and throat swab culture showed conditional pathogen infection. He died of cardiopulmonary failure. Conclusion: In this case, necropsy played a significant role in the final diagnosis of disseminated pulmonary tuberculosis.}, keywords = {Bacillus Calmette-Guérin (BCG),immunodeficiency,Pathogen,infection,Tuberculosis,Vaccination}, url = {https://iji.sums.ac.ir/article_16736.html}, eprint = {https://iji.sums.ac.ir/article_16736_9493014880a1cb2423ea9186d764a2c2.pdf} }