TY - JOUR ID - 16703 TI - Immunological Basis of Neurological Diseases JO - Iranian Journal of Immunology JA - IJI LA - en SN - 1735-1383 AU - Zarei, Mojtaba AD - Department of Health Clinician-Scientist Fellow, Functional Magnetic Resonance Imaging Centre, Department of Clinical Neurology, John Radcliffe Hospital, University of Oxford, OX3 9DU, United Kingdom Y1 - 2004 PY - 2004 VL - 1 IS - 1 SP - 6 EP - 25 KW - Immunology KW - Neurological disease KW - Autoimmune Diseases DO - N2 - Clinical neurology has been traditionally considered as an academic speciality in which the specialist regurgitates his/her knowledge of neurology without being able to do much for the patient. This attitude is no longer acceptable. Surge of information and discoveries in neurosciences within the last two decades translated into therapeutic interventions which is literally life saving in some occasions. Neuroimmunology, without a doubt, has been in the forefront of such discoveries. Just a few decades ago immunology of the nervous system was of little interest because brain was thought to be an immunologically “privileged” organ i.e. inaccessible to cellular and humeral immunity. Today, however, clinical neurologists deal with neurological problem with immunological basis on a daily basis. This article tries to review such diseases and their current therapeutic strategy proceeded by an introduction to CNS immunity. Multiple sclerosis, as one of the most common CNS disease with immunological basis, has been given more attention because of the growing number of affected people in Iran. UR - https://iji.sums.ac.ir/article_16703.html L1 - https://iji.sums.ac.ir/article_16703_f2cf12009912a53b420a32c911658d28.pdf ER -