Volume 21 (2024)
Volume 20 (2023)
Volume 19 (2022)
Volume 18 (2021)
Volume 17 (2020)
Volume 16 (2019)
Volume 15 (2018)
Volume 14 (2017)
Volume 13 (2016)
Volume 12 (2015)
Volume 11 (2014)
Volume 10 (2013)
Volume 9 (2012)
Volume 8 (2011)
Volume 7 (2010)
Volume 6 (2009)
Volume 5 (2008)
Volume 4 (2007)
Volume 2 (2005)
Volume 1 (2004)
Original Article
Molecular Cloning and Expression of Human Gamma Interferon (IFN-g) Full cDNA in Chinese Hamster Ovary (CHO) Cells

Alireza Zamani; Jalil Tavakkol Afshari; Mohammad Yousef Alikhani

Volume 3, Issue 1 , March 2006, Pages 1-8

Abstract
  Background: IFN-g is mostly secreted by activated CD4+ , CD8+ T cells and NK cells. This cytokine has immunomodulatory, anti-cancer and anti-microbial effects and is important for prophylaxis, diagnosis and treatment of chronic infections and cancers. Objective: The purpose of this study was to clone ...  Read More

Original Article
Evaluation of CD64 Expression on Peripheral Blood Neutrophils for Early Detection of Neonatal Sepsis

Minoo Adib; Fakhri Navaei; Farzad Oreizi; Fereshteh Saheb-Fosoul; Vajiheh Ostadi

Volume 3, Issue 1 , March 2006, Pages 9-14

Abstract
  Background: Neonatal sepsis is a life-threatening disease with an incidence of 1 to 10 per 1000 live births and a mortality rate of 15% to 50%. The clinical signs are non-specific and indistinguishable from those caused by a variety of neonatal noninfectious disorders. Objective: The aim of this study ...  Read More

Original Article
Evaluation of Serum Interleukin-18 levels in Helicobacter Pylori-infected Peptic Ulcer Patients and its Association with Bacterial CagA Virulence Factor

Abdollah Jafarzadeh; Mohammad Ali Sajjadi

Volume 3, Issue 1 , March 2006, Pages 15-22

Abstract
  Background: Helicobacter pylori infection is one of the most common gastrointestinal infections worldwide. Predominant T-helper 1 (Th1) responses with increased gamma interferon (IFN- γ) levels have been proposed to play an important role in H. pylori-induced peptic ulcer. However, bacterial factors ...  Read More

Original Article
Angiotensin Converting Enzyme Gene Polymorphism in Iranian Patients with Type 2 Diabetes

Abdol Rahim Nikzamir; Taghi Golmohammadi; Manouchehr Nakhjavani; Mahine Zahraei; Ali Akbar Amirzargar

Volume 3, Issue 1 , March 2006, Pages 23-29

Abstract
  Background: Angiotensin I converting enzyme (ACE) is a Zinc metalloproteinase, converts Ang-I to Ang- II, a pro-inflammatory agent which may contribute to pathophysiology of some diseases like type 2 diabetes. Objective: To investigate the relationship between ACE I/D polymorphism and type 2 diabetes ...  Read More

Original Article
Determination of Hepatitis B Surface Antibody Titer in Vaccinated Children with Major Thalassemia in Kerman-Iran

Ali Asghar Vahidi; Majid Varesvazirian; Ayeh Shamsadini; Sadollah Shamsadini

Volume 3, Issue 1 , March 2006, Pages 30-34

Abstract
  Background: Thalassemia patients are more susceptible to hepatitis than the normal population due to the frequent blood transfusions. Objective: To determine the immune response of children with major ß-thalassemia, by measuring anti-hepatitis B surface antibody (anti-HBs Ab) following the last ...  Read More

Original Article
Sero-surveillance of Measles in Iranian Army Students after Nationwide Revaccination in 2004

Kazem Ahmadi; Gholam Ali Ghorbani

Volume 3, Issue 1 , March 2006, Pages 35-42

Abstract
  Background: Decay of vaccine–induced antibody titres without boosting of the wild measles virus has been well documented. Revaccination against measles has reduced the prevalence of the disease worldwide. Revaccination may cause IgE induced anaphylaxis. Objective: To study measles IgG antibody ...  Read More

Original Article
Seroprevalence of Varicella-Zoster Virus in Children from Shiraz-Iran

Mohammad Motamedifar; Farhad Handijani; Nahal Hadi; Mohammad Kazem Shahkarami; Davoud Mehrabani

Volume 3, Issue 1 , March 2006, Pages 43-46

Abstract
  Background: Varicella–zoster virus (VZV) causes herpes zoster and varicella (Chicken-pox), usually a mild disease which is diagnosed clinically with few complications. However, in neonates and healthy adults it can have a severe presentation. Herpes zoster results from VZV reactivation later in ...  Read More

Original Article
Detection of Toxoplasma Parasitemia by PCR: Does it Correlate with IgG and IgM Antibody Titers?

Behzad Haghpanah; Mansoor Salehi; Shahram Sadri

Volume 3, Issue 1 , March 2006, Pages 47-53

Abstract
  Background: Toxoplasmosis is a zoonotic disease with high seroprevalence worldwide. Several immunological methods have been described for diagnosis of toxoplasmosis. Objective: To determine the parasitemia period in patients infected with toxoplasma using PCR and comparing serological data with molecular ...  Read More