Volume 21 (2024)
Volume 20 (2023)
Volume 19 (2022)
Volume 18 (2021)
Volume 17 (2020)
Volume 16 (2019)
Volume 15 (2018)
Volume 14 (2017)
Volume 13 (2016)
Volume 11 (2014)
Volume 10 (2013)
Volume 9 (2012)
Volume 8 (2011)
Volume 7 (2010)
Volume 6 (2009)
Volume 5 (2008)
Volume 4 (2007)
Volume 3 (2006)
Volume 2 (2005)
Volume 1 (2004)
Original Article
Tumor Associated Mesenchymal Stromal Cells Show Higher Immunosuppressive and Angiogenic Properties Compared to Adipose Derived MSCs

Ladan Langroudi; Zuhair Muhammad Hassan; Masoud Soleimani; Seyed Mahmoud Hashemi

Volume 12, Issue 4 , December 2015, Pages 226-239

Abstract
  Background: Differentiation, migratory properties and availability of Mesenchymal Stromal Cells (MSC) have become an important part of biomedical research. However, the functional heterogeneity of cells derived from different tissues has hampered providing definitive phenotypic markers for these cells. ...  Read More

Original Article
Altered Suppressor Function of Regulatory T Cells in Type 1 Diabetes

Babak Aghili; Ali Akbar Amirzargar; Asadollah Rajab; Ali Rabbani; Arya Sotoudeh; Sara Assadiasl; Bagher Larijani; Ahmad Massoud

Volume 12, Issue 4 , December 2015, Pages 240-251

Abstract
  Background: Type 1 diabetes (T1D) is a T cell mediated autoimmune disease targeting the insulin-producing β cells within pancreatic islets. Autoimmune diseases may develop as a consequence of altered balance between regulatory (Tregs) and autoreactive T cells. Objectives: To evaluate Treg cells ...  Read More

Original Article
Altered Th17/Treg Ratio in Recurrent Miscarriage after Treatment with Paternal Lymphocytes and Vitamin D3: a Double- Blind Placebo-Controlled Study

Mitra Rafiee; Marjan Gharagozloo; Ataollah Ghahiri; Ferdous Mehrabian; Mohammad R. Maracy; Shirin Kouhpayeh; Ina Laura Pieper; Abbas Rezaei

Volume 12, Issue 4 , December 2015, Pages 252-262

Abstract
  Background: Recurrent miscarriage (RM) affects 2-5% of pregnant women. Paternal lymphocyte immunotherapy is a common treatment for RM patients but the outcome has not been consistent. Therefore, combined therapy with other immunosuppressive drugs such as 1 a, 25-dihydroxy-vitamin-D3 (vitamin D3) may ...  Read More

Original Article
H2-EB1 Molecule Alleviates Allergic Rhinitis Symptoms of H2-Eb1 Knockout Mice

Linge Li; Bin Hu; Juan Feng; Yu Zhang; Xi Shou; Yu Tian; Chunrong Jiang; Hua Zhang

Volume 12, Issue 4 , December 2015, Pages 263-273

Abstract
  Background:   H2-EB1 molecule which is the homolog of Human HLA-DRB1 is proposed to be associated with allergic rhinitis (AR). Construction of   H2-Eb1 knockout animal models provides a tool to elucidate the role of H2-EB1 and AR pathogenesis. Objective:   To establish the H2-Eb1 knockout ...  Read More

Original Article
Cationic Immune Stimulating Complexes Containing Soluble Leishmania Antigens: Preparation, Characterization and in Vivo Immune Response Evaluation

Ahmad Mehravaran; Mahmoud Reza Jaafari; Seyed Amir Jalali; Ali Khamesipour; Mohsen Tafaghodi; Mansure Hojatizade; Azam Abbasi; Ali Badiee

Volume 12, Issue 4 , December 2015, Pages 274-287

Abstract
  Background: Cationic immune stimulating complexes (PLUSCOMs) are particulate antigen delivery systems. PLUSCOMs consist of cationic immunostimulatory complexes (ISCOMs) derivatives and are able to elicit in vivo T cell responses against an antigen. Objective: To evaluate the effects of PLUSCOMs containing ...  Read More

Original Article
Ginger Extract Reduces the Expression of IL-17 and IL-23 in the Seraand Central Nervous System of EAEMice

Abdollah Jafarzadeh; Sayyed-Vahab Azizi; Maryam Nemati; Hossain Khoramdel-Azad; Ali Shamsizadeh; Fatemeh Ayoobi; Zahra Taghipour; Zuhair-Mohammad Hassan

Volume 12, Issue 4 , December 2015, Pages 288-301

Abstract
  Background: IL-17/IL-23 axis plays an important role in the pathogenesis of several autoimmune diseases such as experimental autoimmune encephalomyelitis (EAE) and multiple sclerosis (MS). The immunomodulatory properties of ginger are reported in previous studies. Objective: To evaluate the effects ...  Read More

Original Article
Serum Levels of Monocyte Chemoattractant Protein-1 Correlate with Poor Clinical Grades in Cerebral Aneurysms

Abdolkarim Rahmanian; Navideh Mohebali; Ali Haghnegahdar; Eskandar Kamali Sarvestani; Ali Razmkon; Juri Kivelev; Fahim Baghban

Volume 12, Issue 4 , December 2015, Pages 302-310

Abstract
  Background : Ruptured cerebral aneurysms (ICAs) are the most common non-traumatic cause of subarachnoid hemorrhage (SAH) that is associated with life threatening complications such as Vasospasm, Infarction, and Hydrocephalus (HCP). The active participation of macrophage/monocyte-mediated inflammatory ...  Read More

Short Paper
The Effect of Plasma Exchange on the Expression of FOXP3 and RORC2 in Relapsed Multiple Sclerosis Patients

Azam Jamshidian; Mohammad Kazemi; Vahid Shaygannejad; Mansoor Salehi

Volume 12, Issue 4 , December 2015, Pages 311-318

Abstract
  Background: Lack of sufficient information on the mechanism of plasma exchange (PE) therapy in multiple sclerosis (MS), has limited this treatment to individual patients with severe relapses who have been refractory to other treatments. This is while PE is used very successfully as a first-line standard ...  Read More