Volume 21 (2024)
Volume 20 (2023)
Volume 19 (2022)
Volume 18 (2021)
Volume 17 (2020)
Volume 16 (2019)
Volume 15 (2018)
Volume 14 (2017)
Volume 13 (2016)
Volume 12 (2015)
Volume 11 (2014)
Volume 10 (2013)
Volume 9 (2012)
Volume 8 (2011)
Volume 7 (2010)
Volume 6 (2009)
Volume 5 (2008)
Volume 4 (2007)
Volume 3 (2006)
Volume 2 (2005)
Volume 1 (2004)
Effect of Cinnamon and Turmeric Aqueous Extracts on Serum Interleukin-17F Level of High Fructose-Fed Rats

Maryam Sohrabi; Mahdi Alahgholi-Hajibehzad; Zahra Gholami Mahmoodian; Sayed Ali Hosseini Siyar; Alireza Zamani

Volume 15, Issue 1 , March 2018, , Pages 38-46

Abstract
    Background: Studies have indicated that extraweight and obesity induce chronic inflammation, which can lead to other diseases such as cancers. Objective: To evaluate the effects of two weight-lowering and anti-inflammatory agents including cinnamon, and turmeric, on serum levels of interleukin-17 ...  Read More

Tumor Markers in Patients Undergoing Hemodialysis and Kidney Transplantation

Ali Derakhshan; Masoumeh Mohkam; Abbas Ghaderi; Ghamar Hosseini Alhashemi; Mohammad Hossein Fallahzadeh

Volume 1, Issue 1 , June 2004, , Pages 41-47

Abstract
  Objective: To evaluate the effect of dialysis and kidney transplantation on serum levels of several tumor markers such as PSA, AFP, CA125, CA19- 9, CA15-3, CEA and to compare with normal age matched controls. Methods: Between September of 2000 and July of 2001, the following tumor markers: PSA, AFP, ...  Read More

Activity of Dipeptidyl Peptidase-IV/CD26 and Aminopeptidase N/CD13 in Secretome of Mesenchymal Stem Cells after Treatment with LPS and PMA

Khadijeh Ramezani Ali Akbari; Anwar Fathollahi; Seyed Mahmoud Hashemi; Ramin Pouriran; Farshid Yeganeh

Volume 17, Issue 1 , March 2020, , Pages 41-51

https://doi.org/10.22034/iji.2020.80293

Abstract
  Background: Emerging evidence suggests that secretome of mesenchymal stem cells has many anti-inflammatory and regenerative properties, which makes it a suitable candidate for the treatment of autoimmune and degenerative diseases. Dipeptidyl Peptidase-IV (DPP-IV)/CD26 and Aminopeptidase N (APN)/CD13 ...  Read More

Antitetanus Toxoid Antibody Titer of Chronic Hemodialysis Patients in Iran

Mohammad Mahdi Sagheb; Sharareh Sajjadi; Golmehr Sajjady

Volume 5, Issue 1 , March 2008, , Pages 45-50

Abstract
  Background: Patients with end stage renal disease have higher incidence of infection dis-eases that is thought to be related to impaired immune system. Objective: To determine the antitetanus IgG antibody level in Iranian hemodialysis patients with end stage renal disease and to find its association ...  Read More

Infection by Cag A Positive Strains of Helicobacter pylori is Associated with Autoimmune Thyroid Disease in Iranian Patients

Mahmood Soveid; Kazem Hosseini Asl; Gholamhossein Ranjbar Omrani

Volume 9, Issue 1 , March 2012, , Pages 48-52

Abstract
  Background: Infectious agents have been suspected as a triggering factor for development of autoimmune thyroid disease (ATD). Some reports from Western countries have suggested association between Helicobacter pylori (HP) infection and ATD. Objective: To investigate the association of ATD with Cag A ...  Read More

Evaluation of Cellular Immune Response against Purified Antigen 85 in Patients with Tuberculosis

Iraj Nikokar; Manouchehr Makvandi; Mohammad Javad Kajbaf; Ahmad Farajzadeh; Mehdi Mirsaeidi; Eskandar Kamali-Sarvestani; Ali Mostafaie; Kris Huygen

Volume 3, Issue 2 , June 2006, , Pages 70-77

Abstract
  Background: Tuberculosis (TB) remains an important health problem throughout the world. Despite its significance in public health, mechanisms of protective immunity against Mycobacyerium Tuberculosis in humans have not yet been understood. Objective: To evaluate cell mediated immune response against ...  Read More

Ganoderma Lucidum Induces the Expression of CD40/CD86 on Peripheral Blood Monocytes

Kazem Ahmadi; Majid Riazipour

Volume 6, Issue 2 , June 2009, , Pages 87-91

Abstract
  Background: The major immuno-modulating effects of Ganoderma lucidum include mitogenicity and activation of immune effector cells such as T cells, macrophages and natural killer cells resulting in the production of cytokines. Objective: The purpose of this study was to evaluate the expression of CD40 ...  Read More

Inhibitory Killer Cell Immunoglobulin-Like Receptor KIR3DL1 in Combination with HLA-B Bw4iso Protect against Ankylosing Spondylitis

Tahereh Mousavi; Hadi Poormoghim; Maziar Moradi; Nader Tajik; Farhad Shahsavar; Behnam Asadifar

Volume 7, Issue 2 , June 2010, , Pages 88-95

Abstract
  Background: The HLA class I molecules serve as ligands for both T cell receptors and killer cell immunoglobulin-like receptors (KIRs). Objective: We investigated the HLAC and HLA-Bw4 alleles as well as KIRs expression on CD56 positive lymphocytes to evaluate whether these genes and molecules could influence ...  Read More

Stromal Cell Derived Factor-1 Genetic Variation at Locus 801 in Patients with Myasthenia Gravis

Gholam ALi Yousefipour; Mohammad Reza Haghshenas; Sara Yahyazadeh; Nasrollah Erfani

Volume 8, Issue 2 , June 2011, , Pages 90-95

Abstract
  Background: Myasthenia gravis (MG) is the most common disorder of neuromuscular junction in which autoantibodies develop against nicotinic acetylcholine receptor for unknown reasons. The association of immunomodulator genes with different autoimmune disease has been studied in recent years. Objective: ...  Read More

A Flowcytometry Study of CD55 and CD59 Expression on Erythrocytes in Rheumatoid Arthritis Patients

Abbas Ali Pourazar; Alireza Andalib; Farzad Qreizy; Hadi Karimzadeh; Ahmad Ghavami-Nejad; Behshad Pournasr-Khakbaz

Volume 2, Issue 2 , June 2005, , Pages 91-96

Abstract
  Background: Inappropriate activation or blockage of the inhibition of complement system could cause tissue damages in autoimmune diseases particularly rheumatoid arthritis (RA). Defect in complement component regulation may cause damages to tissues, on the other hand, or the damaged tissue might affect ...  Read More

Hyperthermia Increases Natural Killer Cell Cytotoxicity against SW-872 Liposarcoma Cell Line

Shirin Farjadian; Marzie Norouzian; Vahid Younesi; Azin Ebrahimpour; Ramin Lotfi

Volume 10, Issue 2 , June 2013, , Pages 93-102

Abstract
  Background: Although there is convincing data in support of the effectiveness of hyperthermia in tumor therapy, the molecular mechanisms underlying the clinical effects of hyperthermia are still poorly understood. Objective: To investigate natural killer (NK) cell cytotoxicity against heat-treated SW-872 ...  Read More

Association between HLA-DRB1*01 and HLA-Cw*08 and Outcome Following HTLV-I Infection

Houshang Rafatpanah; Vera Pravica; Reza FaridHosseini; Abbas Tabatabaei; Wiliam Ollier; Kay Poulton; Wendy Thomson; Ian Hutchinson

Volume 4, Issue 2 , June 2007, , Pages 94-100

Abstract
  Background: Human T cell lymphotropic virus type I (HTLV-I)-associated myelopa-thy/tropical spastic paraparesis (HAM/TSP) is an inflammatory disease which occurs in less than 2% of HTLV-I -infected individuals. High proviral load, high HTLV-I-specific CD8+ cytotoxic T lymphocyte frequency (CTL) and host ...  Read More

IL-6, IL-10 and IL-17 Gene Polymorphisms in Iranian Women with Recurrent Miscarriage

Motahareh Bahadori; Saeed Zarei; Amir Hassan Zarnani; Omid Zarei; Farah Idali; Reza Hadavi; Mahmood Jeddi-Tehrani

Volume 11, Issue 2 , June 2014, , Pages 97-104

Abstract
  Background: Pro-inflammatory and anti-inflammatory cytokines and polymorphisms of their genes have been described to be involved in the pathogenesis of recurrent miscarriage (RM). Objective: To investigate the association between RM and five polymorphisms of cytokine genes, interleukin 10 (IL-10), (-592 ...  Read More

Natural Oils Enhance IL-10 and IFN-γ Production by Human PBMCs Cultured with Malassezia furfur

Mohammad Ali Rezaee; Yousef Motaharinia; Werya Hosseini; Ali Jalili; Ahmad Rashidi; Bita Mosavi; Ghasem Zamini; Mohammad Reza Rahmani

Volume 9, Issue 2 , June 2012, , Pages 109-118

Abstract
  Background: Malassezia furfur is alipophilic yeast that causes skin disease. Objective: To evaluate the level of IL-10, IFN-γ and IL-12P70 in co-incubation of M. furfur grown on different forms of natural oils with PBMCs of healthy individuals. Methods: PBMCs were obtained from blood samples of ...  Read More

Anticardiolipin Antibody in Patients with Behçet's Disease with and without Vascular Thrombosis

Akbar Rajaee; Mohammad Ali Nazarinia; Seyed Modjtaba Hakim; Mitra Amini; Maryam Ayatollahi; Abbas Ghaderi

Volume 1, Issue 2 , September 2004, , Pages 111-117

Abstract
  Objective: The clinical value of IgG anticardiolipin antibody in patients with Behçet's disease with or without vascular thrombosis was evaluated.   Methods: IgG isotype of anticardiolipin (aCL) antibody was assessed in 40 Behçet's disease (BD) patients with venous or arterial thrombosis, ...  Read More

High Levels of IgA Antibodies to Helicobacter Pylori among Omani Women during Pregnancy and after Delivery

Mohammed Said Al-Balushi; Elias Anthony Said; Sidgi Syed Hasson; Juma Zaid Al-Busaidi; Iman Al-Reesi; Mohammed Idris; Wadha Al-Ghafri; Moza Al-Kalbani; Ali Abdullah Al-Jabri

Volume 13, Issue 2 , June 2016, , Pages 114-123

Abstract
  Background: Helicobacter pylori (H. pylori), is a common infection in pregnant women accompanied by variations in the levels of the IgM, IgA and IgG antibody isotypes. The variations of anti-H. pylori antibodies during and after pregnancy, and the extent of protection they provide to the mother and the ...  Read More

Investigating the Association of IL-17A and IL-17F with Susceptibility to Pre-eclampsia in Iranian Women

Fahimah Anvari; Feryal Dabagh-Gorjani; Mohammad-Sadegh SoltaniZangbar; Eskandar Kamali-Sarvestani; Zahra Malek-Hosseini; Behrouz Gharesi-Fard

Volume 12, Issue 2 , June 2015, , Pages 117-128

Abstract
  Background: Pre-eclampsia (PE) is one of the most important and life-threatening pregnancy disorders that affect at least 3-5% of all pregnancies. Imbalance in helper T cell functions may play a role in predisposing to PE or severity of the disease. Elevated frequencies of Th17 cells in the peripheral ...  Read More

Effect of bortezomib regimens and daratumumab monotherapy on cellular immunity in multiple myeloma patients

Ashraf Kakoo; Taban Rasheed; Mustafa Al-Attar

Volume 18, Issue 2 , June 2021, , Pages 119-129

https://doi.org/10.22034/iji.2021.87547.1812

Abstract
  Background: Treatment with Bortezomib (a proteasome inhibitor) and Daratumumab (DARA, a monoclonal anti CD38 antibody) are effective in patients with multiple myeloma (MM). However, these drugs impair cellular immunity, which may render the patients more prone to infection. Objective: To investigate ...  Read More

Release of sFasL by Monocytes and Lymphocytes Triggered by Betaglucan and Zymosan

Ziba Ghasemi; Babak Farrokhi; Farah Miraghasi; Ardalan Ejaz Ahmad; Nariman Mosaffa

Volume 3, Issue 3 , September 2006, , Pages 121-126

Abstract
  Background: Polysaccharides have long been used as immune-modulators in various pathologic conditions including inflammation and solid malignancies. Objective: To evaluate the effects of Zymosan and Betaglucan on cytotoxic reactions in an effectortarget conjugate system. Methods: Blood was obtained from ...  Read More

Hemin Induces the Activation of NLRP3 Inflammasome in N9 Microglial Cells

Yan Tan; Si-Wei Tan; Bo-Ya Fan; Lei Li; Yuan-Guo Zhou

Volume 15, Issue 2 , June 2018, , Pages 122-132

https://doi.org/10.22034/iji.2018.39376

Abstract
  Background: Hemin is an important sterile component that induces a neuroinflammatory response after intracerebral hemorrhage, in which NLRP3 inflammasome activation has also proved to be involved. Although microglial activation acts as a key contributor in the neuroinflammatory response, the relationship ...  Read More

BALB/c Mice Immunity to Hydatidosis Induced by In-vitro Reared Echinococcus granulosus Adult Worm Antigens

Hamid Reza Rahimi; Tahereh Mohammadzadeh; Seyed Mahmoud Sadjjadi; Bahador Sarkari; Farzaneh Zahabiun

Volume 14, Issue 2 , June 2017, , Pages 123-133

Abstract
  Background: Echinococcosis is a zoonotic parasitic disease caused by the larval stage of Echinococcus granulosus. Several native and recombinant antigens, derived from different stages of E. granulosus life cycle, have been used for vaccine trials. In vitro reared adult worms are good candidates for ...  Read More

GPI-Anchored Fibromodulin as a Novel Target in Chronic Lymphocytic Leukemia: Diagnostic and Therapeutic Implications

Lia Farahi; Fatemeh Ghaemimanesh; Saeideh Milani; Seyed Mohsen Razavi; Reza Hadavi; Ali Ahmad Bayat; Ali Salimi; Mohammad Mehdi Akhondi; Hodjattallah Rabbani

Volume 16, Issue 2 , June 2019, , Pages 127-141

https://doi.org/10.22034/iji.2019.80256

Abstract
  Background: We have previously reported the aberrant expression of Fibromodulin (FMOD) in patients with chronic lymphocytic leukemia (CLL). Although FMOD has been considered as a cytoplasmic or secretory protein, we discovered the cell surface expression of FMOD in leukemic B cells via anchoring with ...  Read More

The Changes of Th17 Cytokines Expression and Its Correlation with Receptor Activator of Nuclear Factor Kappa B Ligand During Orthodontic Tooth Movement

Ting Lin; Li Yang; Weilong Zheng; Bin Zhang

Volume 17, Issue 2 , June 2020, , Pages 137-143

https://doi.org/10.22034/iji.2020.85915.1731

Abstract
  Background: IL-17 is reported to be associated with the pathophysiology of Orthodontic Tooth Movement (OTM) by affecting osteoclastogenesis. Objectives: To explore the changes of Th17 cytokines (IL-17, IL-23, and IL-27) expression and its correlation with receptor activator of nuclear factor kappa ...  Read More

Diversity of T-cell receptor Gene Rearrangements in South Indian Patients with Common Acute Lymphoblastic Leukemia

Natarajan Sudhakar; Nirmala Karunakaran Nancy; Kamalalayam Raghavan Rajalekshmy; Thangarajan Rajkumar

Volume 6, Issue 3 , September 2009, , Pages 141-146

Abstract
  Background: Precursor B-Acute Lymphoblastic Leukemia (precursor B-ALL) oc-curs due to the uncontrolled proliferation of B-lymphoid precursors arrested at a par-ticular stage of B-cell development. Precursor-B-ALL is classified mainly into pro-B-ALL, common-ALL and pre-B-ALL. The Common Acute Lymphoblastic ...  Read More