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Strong Association of CTLA-4 Variation (CT60A/G) and CTLA-4 Haplotypes with Predisposition of Iranians to Head and Neck Cancer

Nasrollah Erfani; Mohammad Reza Haghshenas; Mohammad Ali Hoseini; Seyed Basi Hashemi; Bijan Khademi; Abbas Ghaderi

Volume 9, Issue 3 , September 2012, , Pages 188-198

Abstract
  Background: Variations in Cytotoxic T Lymphocyte Antigen-4 (CTLA-4) affect the expression and function of this protein. Objective: We aimed to investigate the association of +49 A/G (rs231775), +1822 C/T (rs231779) and +6230 A/G (CT60, rs3087243) genetic variations, as well as the merged haplotypes in ...  Read More