Volume 21 (2024)
Volume 20 (2023)
Volume 19 (2022)
Volume 18 (2021)
Volume 17 (2020)
Volume 16 (2019)
Volume 15 (2018)
Volume 14 (2017)
Volume 13 (2016)
Volume 12 (2015)
Volume 11 (2014)
Volume 10 (2013)
Volume 9 (2012)
Volume 8 (2011)
Volume 7 (2010)
Volume 6 (2009)
Volume 5 (2008)
Volume 4 (2007)
Volume 3 (2006)
Volume 2 (2005)
Volume 1 (2004)
Differential WNT Gene Expression in Various Subtypes of Acute Lymphoblastic Leukemia

Ali Memarian; Parvaneh Vosough; Hossein Asgarian-Omran; Mina Tabrizi; Mahdi Shabani; Fazel Shokri

Volume 9, Issue 1 , March 2012, , Pages 61-71

Abstract
  Background: Dysregulation of WNT signaling has been reported in many malignancies. Objective: This study was conducted to investigate the expression pattern of 14 members of the WNT gene family in different immunophenotypic subtypes of ALL. Methods: Semi-quantitative RT-PCR was performed on samples from ...  Read More

Lymphocyte Cytotoxicity of oxLDL in Patients with Atherosclerosis

Mohammad Jafar Mahmoudi; Maryam Mahmoudi; Fereydoon Siassi; Fazel Shokri; Mohammad Reza Eshraghian; Amir Hassan Zamani; Reza Chahardoli; Mona Hedayat; Jalal Khoshnoodi; Hashem Nayeri; Nima Rezaei; Ali-Akbar Saboor-Yaraghi

Volume 8, Issue 1 , March 2011, , Pages 27-33

Abstract
  Background: Atherosclerosis, a chronic inflammatory disease of the vessel wall is characterized by local and systemic immune responses to a variety of antigens. Oxidized low-density lipoprotein (oxLDL) is considered as an important determining factor in the pathogenesis of atherosclerosis. Objective: ...  Read More

Immunologic Basis and Immunoprophy-laxis of RhD Induced Hemolytic Disease of the Newborn (HDN)

Roya Payam Khaja Pasha; Fazel Shokri

Volume 5, Issue 4 , December 2008, , Pages 189-200

Abstract
  RhD antigen is the most immunogenic and clinically significant antigen of red blood cells after ABO system. It has historically been associated with hemolytic disease of the newborn (HDN) which is now routinely prevented by the administration of polyclonal anti-D immunoglobulin. This management of HDN ...  Read More

HLA-DRB1, DQA1 and DQB1 Alleles and Hap-lotypes Frequencies in Iranian Healthy Adult Responders and Non-Responders to Recombi-nant Hepatitis B Vaccine

Ali Akbar Amirzargar; Nilufar Mohseni; Mohammad Ali Shokrgozar; Zohreh Arjang; Nahid Ahmadi; Manijeh Yousefi Behzadi; Amir Amanzadeh; Fazel Shokri

Volume 5, Issue 2 , June 2008, , Pages 92-99

https://doi.org/10.22034/iji.2008.17105

Abstract
  Background: Different studies have demonstrated that a small proportion of healthy individuals receiving the hepatitis B (HB) vaccine do not produce protective levels of anti-HB antibody, a phenomenon which could be linked to certain human leukocyte an-tigen (HLA) class-II alleles or haplotypes. Objectives: ...  Read More

Immunophenotypic Characterization of the Leukemic B-cells from Iranian Patients with Chronic Lymphocytic Leukemia: Association between CD38 Expression and Disease Progression

Mohammad Hojjat Farasangi; Mahmood Jeddi-Tehrani; Seyed Mohsen Razavi; Ramazan Ali Sharifian; Ahmad Shamsian Khoramabadi; Hojatollah Rabbani; Fazel Shokri

Volume 5, Issue 1 , March 2008, , Pages 25-35

Abstract
  Background: Patients with B-cell chronic lymphocytic leukemia (B-CLL) have hetero-geneous clinical courses, thus several biological parameters need to be added to the cur-rent clinical staging systems to predict disease outcome. Recent immunophenotypic stud-ies performed mainly in Western populations ...  Read More

Expression Profile of Wnt Molecules in Leukemic Cells from Iranian Patients with Acute Myeloblastic Leukemia

Ali Memarian; Mahmood Jeddi Tehrani; Parvaneh Vossough; Ramazan Ali Sharifian; Hodjatallah Rabbani; Fazel Shokri

Volume 4, Issue 3 , December 2007, , Pages 145-154

Abstract
  Background: Wnt molecules play a key role in growth, proliferation and development of some embryonic and adult organs as well as hematopoietic stem cells. Wnt signaling pathways are aberrantly activated in many tumor types, including solid tumors and hematologic malignancies. Objective: To investigate ...  Read More

Immunogenicity of a Triple Diphtheria-Tetanus-Whole Cell Pertussis Vaccine in Iranian Preschool Children

Saeed Zarei; Mahmood Jeddi-Tehrani; Mohammad Mehdi Akhondi; Hojjat Zeraati; Tahere Kheirkhah; Morteza Ghazanfari; Fazel Shokri

Volume 4, Issue 2 , June 2007, , Pages 101-109

Abstract
  Background: Immunization against diphtheria, tetanus and pertussis has been applied in Iran since 1950. WHO suggests periodical evaluation of effectiveness of the triple diphtheria-tetanus-whole cell pertussis (DTwP) vaccine, worldwide. Objectives: To determine the immunogenicity of locally manufactured ...  Read More

Immunophenotypic Subtyping of Leukemic Cells from Iranian Patients with Acute Lymphoblastic Leukaemia: Association to Disease Outcome

Hossein Asgarian Omran; Mahdi Shabani; Tahereh Shahrestani; Abdolfattah Sarafnejad; Jalal Khoshnoodi; Parvaneh Vossough; Mohammad Faranoush; Ramzan A. Sharifian; Mahmood Jeddi-Tehrani; Hodjatallah Rabbani; Fazel Shokri

Volume 4, Issue 1 , March 2007, , Pages 15-25

Abstract
  Background: Immunophenotypic characterization of the leukemic cells has been widely used as a tool for diagnosis, classification, stratification and prognosis of leukaemia. Objective: To investigate the immunophenotypic subtype profiles of Iranian patients with acute lymphoblastic leukemia (ALL) and ...  Read More

Over-expression of Wilm’s Tumor Gene 1 (WT1) in Iranian Patients with Acute Myeloblastic Leukemia

Hossein Asgarian; Mahdi Shabani; Parvaneh Vosoogh; Ramazan Ali Sharifian; Soheila Gharagozlou; Jalal Khoshnoodi; Tahereh Shahrestani; Mahin Kordmahin; Abdolfattah Sarrafnejad; Mahmood Jeddi Tehrani; Hodjatallah Rabbani; Fazel Shokri

Volume 2, Issue 4 , December 2005, , Pages 182-190

Abstract
  Background: The Wilm’s tumor gene 1 (WT1) encodes a zinc finger transcription factor that is inactivated in a subset of Wilm’s tumors. It plays a crucial role in growth, proliferation and development of some embryonic and adult organs. WT1 is expressed as a tumor associated antigen (TAA) ...  Read More

Measurement of Affinity Constant of Anti-human IgG Monoclonal Antibodies by an ELISA-based Method

Fatemeh Hajighasemi; Ali Akbar Saboor-Yaraghi; Fazel Shokri

Volume 1, Issue 3 , December 2004, , Pages 154-161

Abstract
  Background: The affinity of an antibody to its antigen is a crucial parameter in its biological activity and performance of an immunoassay such as ELISA. Affinity of most IgG specific MAbs are often determined by methods which require labeling of either antigen or antibody, and are sometimes difficult ...  Read More