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Null Allele Frequencies at HLA-G Locus in Iranian Healthy Subjects

Roghayeh Rahimi; Ahmad Zavaran Hosseini; Fatemeh Yari

Volume 5, Issue 4 , December 2008, , Pages 207-211

Abstract
  Background: HLA-G gene contains 15 alleles including a null allele, HLA-G*0105N. Previous studies have shown that HLA-G*0105N does not encode the complete HLA-G1 or HLA-G5 isoforms but encodes a functional HLA-G protein with the ability to in-hibit NK cell cytolysis. Thus, although the biological functions ...  Read More