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Volume 1 (2004)
Indoleamine 2,3-Dioxygenase and Immunological Tolerance during Pregnancy

Amir Hassan Zarnani; Pouneh Dokouhaki; Mahmood Jeddi-Tehrani

Volume 1, Issue 3 , December 2004, , Pages 143-153

Abstract
  Indoleamine 2,3-dioxygenase (IDO), an enzyme involved in the catabolism of tryptophan, is expressed by a variety of cells and tissues such as macrophages, dendritic cells, cells of the endocrine system and by the placenta. IFN- γ is the main inducer of this enzyme. IDO acts as an important defense ...  Read More