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Anti-inflammatory Effects of PMX205 in Mouse Macrophage Periodontitis Model

Gege Li; Jiahui Pan; Qiuling Tang; Xinchan Liu; Liuran Wang; Yang Meng; Weixian Yu

Volume 15, Issue 2 , June 2018, , Pages 84-96

https://doi.org/10.22034/iji.2018.39373

Abstract
  Background: C5areceptor antagonistPMX205 is a synthetic hexapeptidecapable of blocking C5a-C5a receptor (C5aR) axis by simulating C5a active C-terminal amino acid residues. This hexapeptide presents good anti-inflammatory effects in a myriad inflammation models. The anti-inflammatory effect of PMX205 ...  Read More