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Interleukin-27 Suppresses T Helper-17 Inflammation in Allergic Rhinitis

Hong Ouyang; Jie Cheng; Jingdong Du; Huiyun Gan; Zheng Lu

Volume 17, Issue 4 , December 2020, , Pages 275-282

https://doi.org/10.22034/iji.2020.84871.1675

Abstract
  Background: T helper 17 (Th17) cells and the related cytokines, interleukin (IL)- 17 and IL-23, were proved to play pivotal roles during the development of allergic rhinitis (AR). IL-27, an anti-inflammatory cytokine, has been reported to promote the production of IL-12R and induce Th1 cell responses. ...  Read More