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Mast Cell Numbers in Primary Eosinophilic Colitis are Significantly Higher than in Secondary Tissue Eosinophilia and Normal Controls: a Possible Link to Pathogenesis

Heyam Awad; Ammar Sfaira; Yousef Abu Osba; Mohammad Shahin; Yousef Al- Asa'd; Nooredeen Isbeih; Maha Shomaf; Wasan Hayagneh

Volume 18, Issue 3 , September 2021, , Pages 220-229

https://doi.org/10.22034/iji.2021.88577.1881

Abstract
  Background: Primary Eosinophilic Colitis (PEC) is one of the rare eosinophilic gastrointestinal diseases with a poorly understood pathogenesis. Eosinophilic esophagitis (EE) is the most common and best-understood disease in this category. Activated mast cells (MCs) have a role to play in the tissue damage ...  Read More