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Association of three functional polymorphisms in the NLRP3 gene with susceptibility to rheumatoid arthritis in Iranian population

Mehrdad Nasrollahzadeh Sabet; Navid Nasrabadi; Zahra Jalili; Bahram Pakzad; Saeideh Davar; Naeim Ehtesham; Sima Jafarpour; Meysam Mosallaei; Emran Esmaeilzadeh

Volume 18, Issue 3 , September 2021, , Pages 249-258

https://doi.org/10.22034/iji.2021.89507.1950

Abstract
  Background: Rheumatoid arthritis (RA) is a complex systemic autoimmune disorder with multifactorial nature. Numerous previous studies have shown that several genes are involved in the pathogenesis and increased risk of RA. The Nod-like receptor pyrin domain containing 3 (NLRP3) is involved in the regulation ...  Read More