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TLR9/NF-kB Pathway Regulates Brucella CpG DNA-mediated Cytokine Response in Human Peripheral Blood Mononuclear Cells

Yunzhi Peng; Wenhui Bai; Zhanli Wang; Hui Yu

Volume 18, Issue 4 , December 2021, , Pages 268-278

https://doi.org/10.22034/iji.2021.84578.1665

Abstract
  Background: It was reported that targeting the Toll-like receptor9(TLR9) signaling pathway can be a promising therapeuticstrategy forinterventions in various inflammatory and infectiousdiseases. However,it was not known whether the human TLR9 isresponsive to Brucellacytidine-phosphate-guanosine (CpG) ...  Read More