Volume 19 (2022)
Volume 18 (2021)
Volume 17 (2020)
Volume 16 (2019)
Volume 15 (2018)
Volume 14 (2017)
Volume 13 (2016)
Volume 12 (2015)
Volume 11 (2014)
Volume 10 (2013)
Volume 9 (2012)
Volume 8 (2011)
Volume 7 (2010)
Volume 6 (2009)
Volume 5 (2008)
Volume 4 (2007)
Volume 3 (2006)
Volume 2 (2005)
Volume 1 (2004)
1. Effects of Dendritic Cell Vaccine Activated with Components of Lieshmania Major on Tumor Specific Response

Samaneh Arab; Masoumeh Motamedi; Jamshid Hadjati

Volume 16, Issue 4 , Autumn 2019, , Pages 268-277


  Background: Dendritic cells (DCs) contribute essentially to the outset and course of immune responses. So in patients with malignancy, there have been considerable interests in use of these cells in different interventions. Objective: To evaluate the impact of Leishmania major’s components ...  Read More

2. Whole Tumor Cell Vaccine Adjuvants: Comparing IL-12 to IL-2 and IL-15

Abdolkarim Sheikhi; Abdollah Jafarzadeh; Parviz Kokhaei; Mohammad Hojjat-Farsangi

Volume 13, Issue 3 , Summer 2016, , Pages 148-166

  Cancer immunotherapy (passive or active) involves treatments which promote the ability of the immune system to fight tumor cells. Several types of immunotherapeutic agents, such as monoclonal antibodies, immune checkpoint inhibitors, non-specific immunomodulatory agents, and cancer vaccines are currently ...  Read More

3. sCD30 and sCD40L Detection in Patients with Osteosarcoma, Chondrosarcoma and Ewing Sarcoma

Saeed Solooki; Arash Khozaei; Seyedeh Azra Shamsdin; Mohammad Jafar Emami; Farnaz Khademolhosseini

Volume 10, Issue 4 , Autumn 2013, , Pages 229-237

  Background: Primary malignant bone tumors are heterogeneous groups of neoplasms, which affect mainly children and adolescents. The most common types are Osteosarcoma, Ewing sarcoma and chondrosarcoma. Elevation of sCD30 and sCD40L has been observed in lymphoma, leukemia and autoimmune disorders. Objective: ...  Read More

4. CTLA4 Gene Variants in Autoimmunity and Cancer: a Comparative Review

Abbas Ghaderi

Volume 8, Issue 3 , Summer 2011, , Pages 127-149

  Gene association studies are less appealing in cancer compared to autoimmune diseases. Complexity, heterogeneity, variation in histological types, age at onset, short survival, and acute versus chronic conditions are cancer related factors which are different from an organ specific autoimmune disease, ...  Read More

5. Listeria Monocytogenes Activated Dendritic Cell Based Vaccine for Prevention of Experimental Tumor in Mice

Masoumeh Khamisabadi; Samaneh Arab; Masoumeh Motamedi; Nematollah khansari; Seied Mohammad Moazzeni; Zahra Gheflati; Jamshid Hadjati

Volume 5, Issue 1 , Winter 2008, , Pages 36-44

  Background: The use of dendritic cells (DCs) as a cellular adjuvant provides a promis-ing approach in immunotherapy of cancer. It has been demonstrated that Listeria mono-cytogenes activated DCs pulsed ex vivo with tumor antigens trigger a systemic Th1-biased specific immune response and a single dose ...  Read More

6. Dendritic Cells and Their Role in Cancer Immunotherapy

Ahmad Jalili

Volume 4, Issue 3 , Autumn 2007, , Pages 127-144

  Dendritic cells (DCs) are antigen presenting cells with unique capability to take up and process antigens in the peripheral blood and tissues. They subsequently migrate to draining lymph nodes where they present these antigens and stimulate naive T lympho-cytes. During their life cycle, DCs go through ...  Read More

7. Dendritic Cell Maturation with CpG for Tumor Immunotherapy

Samaneh Arab; Masoumeh Motamedi; Nematollah Khansari; Seied Mohammad Moazzeni; Zahra Gheflati; Jamshid Hadjati

Volume 3, Issue 3 , Summer 2006, , Pages 99-105

  Background: Bacterial DNA has immunostimulatory effects on different types of immune cells such as dendritic cells (DCs). Application of DCs as a cellular adjuvant represents a promising approach in the immunotherapy of infectious disease and cancers. Objectives: To investigate the effect of tumor antigen ...  Read More

8. Monoclonal Antibodies as Therapeutic Agents: Advances and Challenges

Helmout Modjtahedi

Volume 2, Issue 1 , Winter 2005, , Pages 3-20

  Despite the major advances in conventional forms of treatment (i.e. surgical techniques, radiotherapy and chemotherapy) and improved survival rates, cancer is still the second leading cause of death in developing countries. One major limitation of cytotoxic drugs and radiation in the treatment of cancer ...  Read More