%0 Journal Article %T Disseminated Bacillus Calmette-Guérin Disease after BCG Vaccination: A Case Report from China %J Iranian Journal of Immunology %I Shiraz Institute for Cancer Research %Z 1735-1383 %A Ling, Luoya %A Wang, Youqing %A Ding, Ye %A Zheng, Lin %A Qi, Xiaohua %A Jin, Mingjuan %A Chen, Kun %A Xie, Shuyun %D 2015 %\ 03/01/2015 %V 12 %N 1 %P 70-73 %! Disseminated Bacillus Calmette-Guérin Disease after BCG Vaccination: A Case Report from China %K Bacillus Calmette-Guérin (BCG) %K immunodeficiency %K Pathogen %K infection %K Tuberculosis %K Vaccination %R %X Background: Bacillus Calmette-Guérin (BCG) vaccination is recommended for newborn infants worldwide to prevent tuberculosis. However, complications do occur inevitably in a very low rate, among which the most serious is disseminated disease. The disseminated bacillus Calmette–Guérin disease is a rare disease with high fatality, and can be seen among persons with an underlying immunodeficiency. Case presentation: We report a 4-month-old male infant presenting with recurrent fever, an isolated left axillary massand swelling at the site of BCG inoculation. The cellular immune function analysis showed that the value of CD4/CD8 was 0.994, indicating the existence of immunodeficiency.The results of blood culture and throat swab culture showed conditional pathogen infection. He died of cardiopulmonary failure. Conclusion: In this case, necropsy played a significant role in the final diagnosis of disseminated pulmonary tuberculosis. %U https://iji.sums.ac.ir/article_16736_9493014880a1cb2423ea9186d764a2c2.pdf