TY - JOUR ID - 17166 TI - Peripheral, Placental and Cord Cytokines Profile in Spontaneous Labor and Elective Caesarean Section JO - Iranian Journal of Immunology JA - IJI LA - en SN - 1735-1383 AU - Bakheit, Khalid Huseein AU - Bayoumi, Neda Kamal AU - Adam, Ishagh AD - Department of Biochemistry AD - Department of Obstetrics & Gynaecology, Faculty of Medicine, University of Khartoum, Sudan Y1 - 2008 PY - 2008 VL - 5 IS - 3 SP - 185 EP - 188 KW - Levels of IFN-γ KW - IL-4 and IL-10 are influenced by mode of delivery DO - N2 - Background: Cesarean section delivery can lead to much maternal morbidity. Different cytokines have been reported to be influenced by the mode of delivery. Objective: To investigate the influence of mode of delivery on maternal, placental and cord sera of interferon gamma (IFN-γ), interleukin-4 (IL-4) and interleukin-10 (IL-10) levels. Methods: These three cytokines were measured using ELISA in peripheral, placental and cord sera of two groups of women (38 in each group), either delivering vaginally or by elective cesarean section. Results: Concentrations of IFN-γ, IL-4 and IL-10 in the peripheral and placental sera were higher in vaginal delivery, while cord cytokines were not significantly different in the two groups. Cord sera contained significantly less con-centrations of these cytokines than the peripheral and placental sera. Conclusion: It ap-pears that the levels of IFN-γ, IL-4 and IL-10 are influenced by the mode of delivery. UR - https://iji.sums.ac.ir/article_17166.html L1 - https://iji.sums.ac.ir/article_17166_40612804d6cba7e4e2c3ad01e6dd63f7.pdf ER -