TY - JOUR ID - 48525 TI - New-onset Systemic Lupus Erythematosus in a Woman with Previous Lymphoma during Late Pregnancy: a Case Report and Literature Review JO - Iranian Journal of Immunology JA - IJI LA - en SN - 1735-1383 AU - Jiang, Qiaoying AU - Qi, Caixia AU - Yang, Liwei AD - Department of Obstetrics and Gynecology, Zhejiang Provincial People's Hospital, Hangzhou 310016, Zhejiang, China. Y1 - 2022 PY - 2022 VL - 19 IS - 2 SP - 213 EP - 217 KW - Late Pregnancy KW - Lymphoma KW - systemic lupus Erythematosus KW - Thrombocytopenia DO - 10.22034/iji.2022.93584.2239 N2 - Background: Systemic lupus erythematosus (SLE) is most likely to occur during the first and second trimesters of pregnancy. There were few studies focused on the new-onset SLE during the late pregnancy or puerperium. SLE has been considered an important cause of thrombocytopenia. However, lymphoma may also be a cause of thrombocytopenia. Here, we reported a challenging case of new-onset SLE occurred at the gestational age of 33 weeks, and the pregnant woman suffered lymphoma before. Case presentation: A 25-year-old primigravid Chinese woman with a medical history of non-Hodgkin lymphoma (NHL) suffered thrombocytopenia at 30+5 weeks of gestation. Her skin rashes occurred one week later. Her platelet count was decreased progressively. She had been misdiagnosed with the recrudescence of NHL. The final diagnosis of new-onset SLE was confirmed and a cesarean section was performed at the 34th week of pregnancy. Both the pregnant woman and the newborn were cured with good prognosis. Conclusion: SLE should be considered in a pregnant woman with a medical history of malignancy to rule out other diseases, especially the rheumatic immune diseases. UR - https://iji.sums.ac.ir/article_48525.html L1 - https://iji.sums.ac.ir/article_48525_243823d9c5c54a8acdb1573f509e59b1.pdf ER -