Volume 22 (2025)
Volume 21 (2024)
Volume 20 (2023)
Volume 19 (2022)
Volume 18 (2021)
Volume 17 (2020)
Volume 16 (2019)
Volume 15 (2018)
Volume 14 (2017)
Volume 13 (2016)
Volume 12 (2015)
Volume 11 (2014)
Volume 10 (2013)
Volume 9 (2012)
Volume 8 (2011)
Volume 7 (2010)
Volume 6 (2009)
Volume 5 (2008)
Volume 4 (2007)
Volume 3 (2006)
Volume 2 (2005)
Volume 1 (2004)
Design and Cytotoxicity Evaluation of a Cancer-targeting Immunotoxin Based on a Camelid Nanobody-PE Fusion Protein

Mona Khoshbakht; Mohammad Mahdi Forghanifard; Hossein Aghamollaei; Jafar Amani

Volume 21, Issue 4 , December 2024, , Pages 302-315

https://doi.org/10.22034/iji.2024.104052.2878

Abstract
  Background: Developing effective targeted treatment approaches to overcome drug resistance remains a crucial goal in cancer research. Immunotoxins have dual functionality in cancer detection and targeted therapy.Objective: This study aimed to engineer a recombinant chimeric fusion protein by combining ...  Read More

Immunogenic Evaluation of Bivalent Vaccine Candidate against Enterohemorrhagic and Enterotoxigenic Escherichia coli

Ahmad Karimi Rahjerdi; Mahyat Jafari; Mohammad Javad Motamedi; Jafar Amani; Ali Hatef Salmanian

Volume 16, Issue 3 , September 2019, , Pages 200-211

https://doi.org/10.22034/iji.2019.80271

Abstract
  Background: Caused by bacterial, viral, and parasitic pathogens, diarrhea is the second leading cause of death among children under five. Two strains of E. coli, namely Enterotoxigenic, ETEC and Enterohemorrhagic EHEC are the most important causes of this disease in developing countries. EHEC is a major ...  Read More

Designing and Expression of Recombinant Chimeric Protein Containing CtxB and OmpW from Vibrio Cholerae and Evaluation of Its Immunogenicity

Atina Vakili; Seyed Latif Mousavi Gargari; Shahram Nazarian; Jafar Amani

Volume 15, Issue 3 , September 2018, , Pages 207-220

https://doi.org/10.22034/iji.2018.39390

Abstract
  Background: Cholera disease caused by Vibrio cholerae remains a major cause of morbidity and mortality throughout the world. Various strategies with different proteins as immunogens have been tried for vaccine development, none of which have been sufficiently effective to preclude cholera. Chimeric proteins, ...  Read More