Volume 16 (2019)
Volume 15 (2018)
Volume 14 (2017)
Volume 13 (2016)
Volume 12 (2015)
Volume 11 (2014)
Volume 10 (2013)
Volume 9 (2012)
Volume 8 (2011)
Volume 7 (2010)
Volume 6 (2009)
Volume 5 (2008)
Volume 4 (2007)
Volume 3 (2006)
Volume 2 (2005)
Volume 1 (2004)
1. Importance of L. Infantum H2B Recombinant Antigen for Serodiagnosis of Visceral Leishmaniasis

Zahra Rezaei; Gholamreza Pouladfar; Amin Ramezani; Zohreh Mostafavi-Pour; Amin Abbasian; Bahador Sarkari; Bahman Pourabbas

Volume 16, Issue 4 , Autumn 2019, , Pages 311-320

  Background: Visceral leishmaniasis (VL) can lead to death in more than 95% of cases if left untreated. Accurate and early diagnosis has an important role in reducing mortality rate of this disease. Objective: To express recombinant H2B antigen from an Iranian isolate of Leishmania Infantum and evaluate ...  Read More

2. Association of Human Leukocyte Antigens Class I & II with Graves’ Disease in Iranian Population

Zahra Mehraji; Ali Farazmand; Alireza Esteghamati; Sina Noshad; Maryam Sadr; Somayeh Amirzargar; Mir Saeed Yekaninejad; Aliakbar Amirzargar

Volume 14, Issue 3 , Summer 2017, , Pages 223-230

  Background: Graves’ disease (GD), a highly rampant autoimmune disorder of the thyroid gland, is responsible for 60-80% of the clinical cases of hyperthyroidism. Over the past decades, genetic association studies have identified several GD susceptibility loci in CTLA-4, TSHR and major histocompatibility ...  Read More

3. A Leishmania infantum FML-ELISA for the Detection of Symptomatic and Asymptomatic Canine Visceral Leishmaniasis in an Endemic Area of Iran

Behnam Mohammadi-Ghalehbin; Gholam Reza Hatam; Bahador Sarkari; Mehdi Mohebali; Zabih Zarei; Mansoureh Jaberipour; Shahab Bohlouli

Volume 8, Issue 4 , Autumn 2011, , Pages 244-250

  Background: Visceral leishmaniasis (VL) is caused by Leishmania infantum in Mediterranean basin and is an endemic disease in some parts of Iran. Canines are the main reservoirs of VL in most of the endemic areas. Different serological methods have been introduced for diagnosis of canine visceral leishmaniasis ...  Read More

4. Null Allele Frequencies at HLA-G Locus in Iranian Healthy Subjects

Roghayeh Rahimi; Ahmad Zavaran Hosseini; Fatemeh Yari

Volume 5, Issue 4 , Autumn 2008, , Pages 207-211

  Background: HLA-G gene contains 15 alleles including a null allele, HLA-G*0105N. Previous studies have shown that HLA-G*0105N does not encode the complete HLA-G1 or HLA-G5 isoforms but encodes a functional HLA-G protein with the ability to in-hibit NK cell cytolysis. Thus, although the biological functions ...  Read More

5. Analysis of Human Leukocyte Antigen class II Gene Polymorphism in Iranian Patients with Papillon-Lefevre Syndrome: a Family Study

Shirin Farjadian; Mehrdad Lotfazar; Abbas Ghaderi

Volume 5, Issue 3 , Summer 2008, , Pages 171-176

  Background: Papillon-Lefevre syndrome (PLS) is a rare autosomal recessive disorder characterized by palmoplantar hyperkeratosis and early development of aggressive pe-riodontitis. Although cathepsin C (CTSC) gene mutations have been established in about 70-80% of PLS patients, it is assumed that the ...  Read More

6. HLA Class I Gene Polymorphism in Iranian Patients with Papillon-Lefevre Syndrome

Shirin Farjadian; Nasrin Kiyanimanesh; Abbas Abbaszadegan; Mehrdad Lotfazar

Volume 4, Issue 4 , Autumn 2007, , Pages 241-245

  Background: Papillon-Lefevre Syndrome (PLS) is a rare autosomal recessive disorder characterized by diffused palmoplantar keratoderma and severe periodontitis. Increased susceptibility to infections due to impairment of the immune system is considered to be involved in pathoetiology of this disease. ...  Read More

7. HLA class II Genetic Diversity in Arabs and Jews of Iran

Shirin Farjadian; Abbas Ghaderi

Volume 4, Issue 2 , Spring 2007, , Pages 85-93

  Background: Anthropological studies based on highly polymorphic HLA genes pro-vide useful information for bone marrow donor registry, forensic medicine, disease as-sociation studies, as well as designing peptide vaccines against tumors, and infectious or autoimmune diseases. Objective: This study was ...  Read More

8. Iranian Lurs Genetic Diversity: An Anthropological View Based on HLA Class II Profiles

Shirin Farjadian; Abbas Ghaderi

Volume 3, Issue 3 , Summer 2006, , Pages 106-113

  Background: HLA genes are highly polymorphic and certain alleles are frequent only in specific populations. Therefore, HLA is a unique tool for studying the genetic relationship between different populations. Iranians are ethnically diverse people and one of the major ethnic groups in Iran is Lur population ...  Read More

9. Determination of Soluble HER-2/neu (sHER-2/neu) in Iranian Patients with Lung Cancer

Seyyed Mohammad Ali Ghayumi; Kambiz Aghasadeghi; Mehrnoosh Dorouchi; Abbas Ghaderi

Volume 3, Issue 2 , Spring 2006, , Pages 61-65

  Background: The HER-2/neu gene is located on chromosome 17q21 and encodes a 185-kDa transmembrane glycoprotein with tyrosine kinase activity reported to be released in soluble form in various malignancies. Objective: To evaluate the clinical significance of soluble Her-2/neu as a diagnostic marker in ...  Read More

10. Seroprevalence of Varicella-Zoster Virus in Children from Shiraz-Iran

Mohammad Motamedifar; Farhad Handijani; Nahal Hadi; Mohammad Kazem Shahkarami; Davoud Mehrabani

Volume 3, Issue 1 , Winter 2006, , Pages 43-46

  Background: Varicella–zoster virus (VZV) causes herpes zoster and varicella (Chicken-pox), usually a mild disease which is diagnosed clinically with few complications. However, in neonates and healthy adults it can have a severe presentation. Herpes zoster results from VZV reactivation later in ...  Read More

11. Determination of Hepatitis B Surface Antibody Titer in Vaccinated Children with Major Thalassemia in Kerman-Iran

Ali Asghar Vahidi; Majid Varesvazirian; Ayeh Shamsadini; Sadollah Shamsadini

Volume 3, Issue 1 , Winter 2006, , Pages 30-34

  Background: Thalassemia patients are more susceptible to hepatitis than the normal population due to the frequent blood transfusions. Objective: To determine the immune response of children with major ß-thalassemia, by measuring anti-hepatitis B surface antibody (anti-HBs Ab) following the last ...  Read More