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1. Multiple Myeloma Bone Marrow Mesenchymal Stromal Cells Inhibit CD8+ T Cell Function in a Process that May Implicate Fibroblast Activation Protein α

Yadan Wang; Xiaofei Wu; Yu Hu

Volume 16, Issue 4 , Autumn 2019, , Pages 278-290

http://dx.doi.org/10.22034/iji.2019.80279

Abstract
  Background: Multiple myeloma (MM) is a malignant plasma cell proliferative disorder with limited immunotherapy treatment because of T cell dysfunction. Objective: To investigate the immunomodulatory function of bone marrow mesenchymal stromal cells (MM-BMSCs) on CD8+ T cells. Methods: Proliferation and ...  Read More