Volume 16 (2019)
Volume 15 (2018)
Volume 14 (2017)
Volume 13 (2016)
Volume 12 (2015)
Volume 11 (2014)
Volume 10 (2013)
Volume 9 (2012)
Volume 8 (2011)
Volume 7 (2010)
Volume 6 (2009)
Volume 5 (2008)
Volume 4 (2007)
Volume 3 (2006)
Volume 2 (2005)
Volume 1 (2004)

Aim and scope:
The Iranian Journal of Immunology (I.J.I) is an internationally disseminated peer-reviewed publication and publishes a broad range of experimental and theoretical studies concerned with all aspects of immunology.

Types of papers accepted:
The Journal will welcome original and review articles on basic and clinical Immunology, Immunogenetics, Transplantation Immunology, Immunohematology, Cancer Immunology, and Allergy. The Journal will also welcome short papers and letters to the Editor.

Iranian Journal of Immunology is indexed in the following indexing systems: 

  • Web of Science (ISI)
  • EMNursing
  • Cambridge Scientific Abstracts
  • Chemical Abstracts
  • Global Health
  • Index Medicus for Eastern Mediterranean Region (IMEMR)

IJI, is an official publication of the Iranian Society for Immunology and Allergy (ISIA), which is published by Shiraz Institute for Cancer Research, Shiraz University of Medical Sciences (SUMS), Shiraz, Iran.

Original Article
1. Prognostic Impact of Circulating CD28 Negative Suppressor T Cells and Memory B Cells on Treatment Outcomes of Patients with Breast Cancer

Asmaa M. Zahran; Asmaa S. Shaltout; Hussein Fakhry; Ola N. Abdel Fattah; Doaa F. Temerik; Salah M. Khalaf; Amal Rayan

Volume 17, Issue 2 , Spring 2020, Pages 95-110


  Background: It has been suggested that routine assessment and quantification of different lymphocyte subsets can provide clinically meaningful prognostic information in breast cancer (BC). Objective: To determine the relationship between peripheral blood lymphocyte subsets and pathological parameters ...  Read More

Original Article
2. Toward an Alum Free Mono-Component Monovalent Pertussis Vaccine: A Cytokine Response Assay

Hossein Forghani; Mahin Jamshidi Makiani; Hossein Zarei Jaliani; Seyed Mohsen Zahraei; Seyedeh Mahdieh Namayandeh; Parisa Khani

Volume 17, Issue 2 , Spring 2020, Pages 111-120


  Background: Current evidence indicates the resurgence of whooping cough despite high coverage of whole-cell (wP) and acellular (aP) pertussis vaccines. Objective: To investigate the cytokine response to a genetically inactivated protein containing the S1 subunit of pertussis toxin (PTS1) with and without ...  Read More

Original Article
3. In-Silico Analysis and Protective Efficacy of the PcrV Recombinant Vaccine against Pseudomonas Aeruginosa in the Burned and PA-Infected BALB/c Mouse Model

Mohammad Hadi Fakoor; Parviz Owlia; Seyed Latif Mousavi gargari; Azar Sabokbar

Volume 17, Issue 2 , Spring 2020, Pages 121-136


  Background: Pseudomonas aeruginosa is considered as the most severe cause of infections in burn patients and pneumonia infections. Objective: To study the protective effects of recombinant protein vaccine harboring the PcrV of P. aeruginosa in the mouse model of burn and respiratory infections. Methods: ...  Read More

Original Article
4. The Changes of Th17 Cytokines Expression and Its Correlation with Receptor Activator of Nuclear Factor Kappa B Ligand During Orthodontic Tooth Movement

ting lin; li yang; weilong zheng; bin zhang

Volume 17, Issue 2 , Spring 2020, Pages 137-143


  Background: IL-17 is reported to be associated with the pathophysiology of Orthodontic Tooth Movement (OTM) by affecting osteoclastogenesis. Objectives: To explore the changes of Th17 cytokines (IL-17, IL-23, and IL-27) expression and its correlation with receptor activator of nuclear factor kappa ...  Read More

Original Article
5. Fetuin-A and Interleukine-8 in Children with the Clinical Remission of Type 1 Diabetes

Aleksandra Pyziak-Skupien; Katarzyna Bobeff; Krystyna Wyka; Katarzyna Banach; Beata Malachowska; Wojciech Fendler; Agnieszka Szadkowska; Wojciech Mlynarski; Agnieszka Zmyslowska

Volume 17, Issue 2 , Spring 2020, Pages 144-153


  Background: Clinical partial remission (CPR) in most patients with type 1 diabetes (T1D) is observed shortly after clinical diagnosis. Increasing body weight and impaired insulin sensitivity may play a role in the pathogenesis of CPR. Several cytokines can also participate in the development of insulin ...  Read More

Original Article
6. Exposure of 1800 MHz Radiofrequency with SAR 1,6 W/kg Caused a Significant Reduction in CD4+ T Cells and Release of Cytokines In-Vitro

Maimun Zulhaidah Arthamin; Anis Sulalah; Resvina -; Chomsin Widodo; Agustina Tri Endharti; Edi Widjajanto; Tedy Juliandhy

Volume 17, Issue 2 , Spring 2020, Pages 154-166


  Background: Although there have been many studies investigating the effects of electromagnetic fields on humans cells and tissues, the effects of radiofrequency electromagnetic fields exposure on the cells of the immune system are still controversial. Objective: To investigate the effects of 1800 MHz ...  Read More

Case Report
7. Immune-Related Adverse Events Mimicking Behcet's Disease in a Gastric Cancer Patient Following Camrelizumab Treatment

sha sha zhang; Dong Wang; Ping an Ding; Yu fei Zhao; Xiao yun Zhang; Qun Zhao

Volume 17, Issue 2 , Spring 2020, Pages 167-171


  Background: Anti-programmed cell death 1(anti-PD-1) antibodies are immune checkpoint inhibitors (ICIs) used as a treatment option for a number of cancers to expand lifespan. However, the toxicity caused by ICIs is often unpredictable and can be occasionally life-threatening. Objective: To evaluate the ...  Read More

Letter To The Editor
8. Letter to the Editor: Coexistence of Autoimmune Lymphoproliferative Syndrome and Familial Mediterranean Fever

Sultan Aydin Koker; Nesrin Gulez; Frédéric Rieux-Laucat; Ferah Genel; Canan Vergin; Capucine Picard

Volume 17, Issue 2 , Spring 2020, Pages 172-174


  Autoimmune lymphoproliferative syndrome (ALPS) is a rare inherited disorder of apoptosis, most commonly due to mutations in the FAS (TNFRSF6) gene. ALPS caused by defective lymphocyte homeostasis is characterized by non-malignant lymphoproliferation that often improves with age and is an autoimmune disease, ...  Read More

1. Airway Inflammatory Biomarker: Could It Tailor the Right Medications for the Right Asthmatic Patient?

Magdy Mohamed Zedan; Amal Mohamed Osman; Wafaa Nabil Laimon; Mohamed Magdy Zedan; Nermin Youssef Abo-elkheir; Ahmed Zaki

Volume 13, Issue 2 , Spring 2016, , Pages 70-88

  Asthma is a heterogeneous disease, in which asthmatic patients present with different clinical phenotypes, variable endotypes, and different response to asthma medicines. Thus, we are faced with an asthma paradox; asthma is diagnosed subjectively by clinical history and treated with biologically active ...  Read More

2. Efficiency and Impact of Positive and Negative Magnetic Separation on Monocyte Derived Dendritic Cell Generation

Marek Fol; Magdalena Kowalewicz-Kulbat; El ż bieta Ograczyk; Marcin W ł odarczyk; Krzysztof Krawczyk

Volume 13, Issue 2 , Spring 2016, , Pages 132-140

  Background: The immunomagnetic separation technique is the basis of monocyte isolation and further generation of monocyte-derived dendritic cells. Objective: To compare the efficiency of monocyte positive and negative separation, concentration of beads, and their impact on generated dendritic cells. ...  Read More

3. High Levels of IgA Antibodies to Helicobacter Pylori among Omani Women during Pregnancy and after Delivery

Mohammed Said Al-Balushi; Elias Anthony Said; Sidgi Syed Hasson; Juma Zaid Al-Busaidi; Iman Al-Reesi; Mohammed Idris; Wadha Al-Ghafri; Moza Al-Kalbani; Ali Abdullah Al-Jabri

Volume 13, Issue 2 , Spring 2016, , Pages 114-123

  Background: Helicobacter pylori (H. pylori), is a common infection in pregnant women accompanied by variations in the levels of the IgM, IgA and IgG antibody isotypes. The variations of anti-H. pylori antibodies during and after pregnancy, and the extent of protection they provide to the mother and the ...  Read More

4. Correlation of Early and Late Ejection Fractions with CCL5 and CCL18 Levels in Acute Anterior Myocardial Infarction

Mahdi Sajedi Khania; Alireza Abdi Ardekan; Shahdad Khosropana; Mehrnoosh Doroudchi

Volume 13, Issue 2 , Spring 2016, , Pages 100-113

  Background: Acute Myocardial Infarction (AMI) is the leading cause of disability and death in Iran and many other countries. Objective: To investigate the prognostic value of CCL5 and CCL18 in patients with acute myocardial ischemia. Methods: In this cohort study we recruited and followed 50 patients ...  Read More

5. Identification of the Rare, Four Repeat Allele of IL-4 Intron-3 VNTR Polymorphism in Indian Populations

Henu Kumar Verma; Aditya Nath Jha; Prafulla Kumar khodiar; Pradeep Kumar Patra; Lakkakula Venkata Kameswara Subrahmanya Bhaskar

Volume 13, Issue 2 , Spring 2016, , Pages 124-131

  Background: Cytokines are cell signaling molecules which upon release by cells facilitate the recruitment of immune-modulatory cells towards the sites of inflammation. Genetic variations in cytokine genes are shown to regulate their production and affect the risk of infectious as well as autoimmune diseases. ...  Read More

Shiraz Institute for Cancer Research

  Abbas Ghaderi, Ph.D.

Associate Editor:
  Mehrnoosh Doroudchi, Ph.D.

Assistant Editor:
  Morvarid Asadipour, M.Sc.   Mahyar Malekzadeh

Print ISSN: 1735-1383

Online ISSN: 1735-367X

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