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Immunological Properties of Exotoxin A Toxoid - Detoxified Lipopolysaccharide - Gold Nanoparticles Conjugate Against Pseudomonas aeruginosa Infection

Faezeh Najafzadeh; Asghar Tanomand; Azam Hadadi; Jafar Majidi

Volume 18, Issue 4 , December 2021, , Pages 292-303

https://doi.org/10.22034/iji.2021.87816.1832

Abstract
  Background: Pseudomonas aeruginosa is an important opportunistic pathogen, especially in patients with compromised host defense. Objective: To prepare the conjugate of detoxified lipopolysaccharide (D-LPS) and exotoxin A toxoid (T-ETA) from P. aeruginosa in gold nanoparticles (Au NPs) in a mice model. ...  Read More