Volume 18 (2021)
Volume 17 (2020)
Volume 16 (2019)
Volume 15 (2018)
Volume 14 (2017)
Volume 13 (2016)
Volume 12 (2015)
Volume 11 (2014)
Volume 10 (2013)
Volume 9 (2012)
Volume 8 (2011)
Volume 7 (2010)
Volume 6 (2009)
Volume 5 (2008)
Volume 4 (2007)
Volume 3 (2006)
Volume 2 (2005)
Volume 1 (2004)
1. Recombinant Production and One Step Purification of IL-1Ra in Escherichia coli and Evaluation its IL-1 Antagonizing Efficacy

Roya Adelnia; Fatemeh Shafiee

Volume 18, Issue 2 , Spring 2021, , Pages 141-149


  Background: Anakinra (Kineret®), an IL-1 receptor antagonist, is the first FDA approved biologic drug for antagonizing IL-1 effects in patients with Rheumatoid arthritis. Notably, the less expensive production of this drug might help reduce the final therapeutic costs. Objectives: This study aimed ...  Read More

2. Serum Level of Soluble Lymphocyte-Activation Gene 3 Is Increased in Patients with Rheumatoid Arthritis

Nayyereh Saadati; Mandana khodashahi; Zahra Rezaieyazdi; Maryam Sahebari; Zeinab Saremi; Saeed Mohammadian Haftcheshmeh; Houshang Rafatpanah; Maryam Salehi

Volume 17, Issue 4 , Autumn 2020, , Pages 324-332


  Background: Rheumatoid arthritis (RA) is described as a systemic and chronic autoimmune disease characterized by inflammatory polyarthritis. Lymphocyte-activation gene 3 (LAG3) is a membrane glycoprotein expressed on activated, exhausted, and regulatory T cells. LAG3 plays a major role in the function ...  Read More

4. Effect of TNF-α Blockade in Gingival Crevicular Fluid on Periodontal Condition of Patients with Rheumatoid Arthritis

Zeinab Kadkhoda; Aliakbar Amirzargar; Zahra Esmaili; Mahdi Vojdanian; Solmaz Akbari

Volume 13, Issue 3 , Summer 2016, , Pages 197-203

  Background: Periodontitis and rheumatoid arthritis (RA) share a number of clinical and pathologic features, one of which is the presence of the tumor necrosis factor alpha (TNF-α)-induced bone resorption that is involved in the pathogenesis of both. Objectives: To investigate the effect of TNF-α ...  Read More

5. Patients with Active Rheumatoid Arthritis Have Lower Frequency of nTregs in Peripheral Blood

Hamid-Reza Zare; Mojtaba Habibagahi; Akbar Vahdati; Zahra Habibagahi

Volume 12, Issue 3 , Summer 2015, , Pages 166-175

  Background: Patients with rheumatoid arthritis (RA) suffer from wide ranges of autoimmune reactions in joints. The mechanism of which is generally unknown and maybe associated with Treg deregulation. Objective: To compare the frequency of nTregs in peripheral blood of patients with active rheumatoid ...  Read More

6. Serum Levels of TNF-α, TNF-αRI, TNF-αRII and IL-12 in Treated Rheumatoid Arthritis Patients

Ali Asghar Ebrahimi; Hamid Noshad; Shahram Sadreddini; Mohammad Saeid Hejazi; Yashar Mohammadzadeh Sadigh; Yashar Eshraghi; Morteza Ghojazadeh

Volume 6, Issue 3 , Summer 2009, , Pages 147-153

  Background: Rheumatoid arthritis (RA) is a chronic multisystem autoimmune disease common in all races and ethnics. Cytokines and cytokines receptors play an important role in RA pathogenesis and clinical presentation. Objective: To investigate the serum levels of TNF-α, TNF-α RI, TNF-α ...  Read More

7. A Flowcytometry Study of CD55 and CD59 Expression on Erythrocytes in Rheumatoid Arthritis Patients

Abbas Ali Pourazar; Alireza Andalib; Farzad Qreizy; Hadi Karimzadeh; Ahmad Ghavami-Nejad; Behshad Pournasr-Khakbaz

Volume 2, Issue 2 , Spring 2005, , Pages 91-96

  Background: Inappropriate activation or blockage of the inhibition of complement system could cause tissue damages in autoimmune diseases particularly rheumatoid arthritis (RA). Defect in complement component regulation may cause damages to tissues, on the other hand, or the damaged tissue might affect ...  Read More