Iranian Journal of Immunology

Relapsing Polychondritis Associated with Miscellaneous Ocular Symptoms and Increased IgA: a Case Report

Document Type : Case Report

Authors

Yu Zhang 1
Li Zhang 2
Zhen zhen Wu 1
Jianping Tang 1
Xuan Wang 1

1 Department of Rheumatology and Immunology, Tongji Hospital, Tongji University School of Medicine, Shanghai, People’s Republic of China.

2 Department of Ophthalmology, Tongji Hospital, Tongji University School of Medicine, Shanghai, People’s Republic of China.

https://doi.org/10.22034/iji.2022.91845.2110
Abstract
A male patient had suffered miscellaneous ocular symptoms for 20 years with auricular dysmorphosis and was diagnosed with Relapsing Polychondritis (RP) in the ear, nose, joints, and costal cartilage. The patient lost his vision owing to recurrent ocular symptoms for decades. He presented an increased IgA and was diagnosed with monoclonal gammopathy of undetermined significance (MGUS) and treated by prednisone and cyclophosphamide. His ocular symptoms relieved and serum IgA decreased after six months. In conclusion, RP is a systemic disease with a wide range of clinical symptoms and may lead to serious complications.

Keywords

Gammopathy of Undetermined Significance
Hematological Malignancies
IgA
Miscellaneous Ocular Symptoms, Monoclonal
Relapsing Polychondritis
Iranian Journal of Immunology
Volume 19, Issue 1
Winter 2022
Pages 110-114

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