Volume 17 (2020)
Volume 16 (2019)
Volume 15 (2018)
Volume 14 (2017)
Volume 13 (2016)
Volume 12 (2015)
Volume 11 (2014)
Volume 10 (2013)
Volume 9 (2012)
Volume 8 (2011)
Volume 7 (2010)
Volume 6 (2009)
Volume 5 (2008)
Volume 4 (2007)
Volume 3 (2006)
Volume 2 (2005)
Volume 1 (2004)
1. Effect of Cytomegalovirus Recombinant Phosphoprotein 150 (pp150) on Function and Maturation of Murine Dendritic Cells: an In-Vitro Study

Yousef Nikmanesh; Shohreh Shahmahmoodi; Ramin Yaghobi; Sayed Mahdi Marashi; Mahmood Mahmoudi; Mahdokht Hossein Aghdaie; Maryam Khosravi; Mohammad Hossein Karimi

Volume 17, Issue 1 , Winter 2020, , Pages 26-40


  Background: Tegument protein pp150 of cytomegaloviruses (CMVs) plays a vital role in all stages of viral life cycle, representing the most important tegument protein candidate for HCMV treatment. However, the exact role of pp150 in immune regulation is yet to be elucidated. Objective: To examine the ...  Read More

2. CD40 Knocked Down Tolerogenic Dendritic Cells Decrease Diabetic Injury

Aziz Mahmoudzadeh; Ali Akbar Pourfathollah; Mohammad Hossein Karimi; Seyed Mohammad Moazzeni

Volume 14, Issue 4 , Autumn 2017, , Pages 270-280

  Background: Type-1 diabetes (T1D) is an autoimmune disease in which T lymphocytes destroy insulin-producing β-cells. Control of self-reactive T lymphocytes and recovery of diabetic injury is the end point of T1D. Objective: To investigate generation of tolerogenic dendritic cells (tolDCs) as an ...  Read More

3. Immunomodulatory Effects of Mice Mesenchymal Stem Cells on Maturation and Activation of Dendritic Cells

Ladan Sadeghi; Eskandar Kamali-Sarvestani; Negar Azarpira; Mehrdad Shariati; Mohammad Hossein Karimi

Volume 11, Issue 3 , Summer 2014, , Pages 177-188

  Background: Mesenchymal stem cells (MSCs) possess a wide range of immunomodulatory functions mostly in immune cells including dendritic cells (DCs). DCs are the key cells in the immune response and play an important role in initiating cell-mediated immunity. Objective: To evaluate the immunomodulatory ...  Read More

4. Interleukin-17 Gene Expression and Serum Levels in Acute Rejected and non-Rejected Liver Transplant Patients

Afsoon Afshari; Ramin Yaghobi; Mohammad Hossein Karimi; Mojtaba Darbooie; Negar Azarpira

Volume 11, Issue 1 , Winter 2014, , Pages 29-39

  Background: Interleukin-17 (IL-17), as a potent proinflammatory cytokine, has a critical role in post liver transplant outcomes. However, there is not much information about the effects of IL-17 cytokine on acute liver rejection. Objective: To evaluate the role of IL-17 in post-liver transplant acute ...  Read More

5. Interleukin-17 Gene Expression and Serum Levels in Children with Severe Asthma

Soheila Alyasin; Mohammad Hossein Karimi; Reza Amin; Maryam Babaei; Sepideh Darougar

Volume 10, Issue 3 , Summer 2013, , Pages 177-185

  Background: IL-17 is a major cytokine player in T cell mediated leukocyte associated inflammation. IL-17 is also recognized to participate in the pathophysiology of asthma. Objective: To determine the role of IL-17 in predicting severe asthma. Methods: We obtained serum samples from asthmatic children ...  Read More

6. Evaluation of the Immunomodulatory Effect of Curdlan on Maturation and Function of Mouse Spleen-Derived Dendritic Cells

Mohammad Hashem Soltani; Tahereh Kalantari; Mohammad Hossein Karimi; Nasrollah Erfani; Eskandar Kamali Sarvestani

Volume 9, Issue 3 , Summer 2012, , Pages 168-174

  Background: T helper 1 and T helper 17 cells play important roles in immunity against foreign invaders. Differentiation of these Th subsets is affected by state of maturation and cytokines that are produced by dendritic cells (DCs). Curdlan is a linear (1→3)-β- glucan and has shown activity ...  Read More

7. The Efficiency of CD40 Down Regulation by siRNA and Antisense ODN: Comparison of Lipofectamine and FuGENE6

Padideh Ebadi; Mohammad Hossein Karimi; Ali Akbar Pourfathollah; Saheb Ghadam Lotfi; Zahra Soheila Soheili; Shahram Samiee; Smerdis Hajati; Fatemeh Nadali; Bita Geramizadeh; Seyyed Mohammad Moazzeni

Volume 6, Issue 1 , Winter 2009, , Pages 1-11

  Background: Dendritic cells (DCs) are ideal accessory cells in the field of gene therapy. Delivery of DNA and siRNA into mammalian cells is a useful technique in treating various diseases caused by single gene defects. Selective gene silencing by small interfering RNAs (siRNAs) and antisense oligodeoxynucleotides ...  Read More