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Volume 11 (2014)
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1. Islet Amyloid Polypeptide is not a Target Antigen for CD8+ T-Cells in Type 2 Diabetes

Fathollah Kalantar; Mohammad Hossein Dabbaghmanesh; Emanuela Martinuzzi; Mohsen Moghadami; Zahra Amirghofran

Volume 11, Issue 1 , Winter 2014, , Pages 1-12

Abstract
  Background: Type 2 diabetes (T2D) is a chronic metabolic disorder in which beta-cells are destroyed. The islet amyloid polypeptide (IAPP) produced by beta-cells has been reported to influence beta-cell destruction. Objective: To evaluate if IAPP can act as an autoantigen and therefore, to see if CD8 ...  Read More