Volume 21 (2024)
Volume 20 (2023)
Volume 19 (2022)
Volume 18 (2021)
Volume 17 (2020)
Volume 16 (2019)
Volume 15 (2018)
Volume 14 (2017)
Volume 13 (2016)
Volume 12 (2015)
Volume 11 (2014)
Volume 10 (2013)
Volume 9 (2012)
Volume 8 (2011)
Volume 7 (2010)
Volume 6 (2009)
Volume 5 (2008)
Volume 4 (2007)
Volume 3 (2006)
Volume 2 (2005)
Volume 1 (2004)
Effects of Dendritic Cell Vaccine Activated with Components of Lieshmania Major on Tumor Specific Response

Samaneh Arab; Masoumeh Motamedi; Jamshid Hadjati

Volume 16, Issue 4 , December 2019, , Pages 268-277

https://doi.org/10.22034/iji.2019.80278

Abstract
  Background: Dendritic cells (DCs) contribute essentially to the outset and course of immune responses. So in patients with malignancy, there have been considerable interests in use of these cells in different interventions. Objective: To evaluate the impact of Leishmania major’s components ...  Read More

Whole Tumor Cell Vaccine Adjuvants: Comparing IL-12 to IL-2 and IL-15

Abdolkarim Sheikhi; Abdollah Jafarzadeh; Parviz Kokhaei; Mohammad Hojjat-Farsangi

Volume 13, Issue 3 , September 2016, , Pages 148-166

Abstract
  Cancer immunotherapy (passive or active) involves treatments which promote the ability of the immune system to fight tumor cells. Several types of immunotherapeutic agents, such as monoclonal antibodies, immune checkpoint inhibitors, non-specific immunomodulatory agents, and cancer vaccines are currently ...  Read More

sCD30 and sCD40L Detection in Patients with Osteosarcoma, Chondrosarcoma and Ewing Sarcoma

Saeed Solooki; Arash Khozaei; Seyedeh Azra Shamsdin; Mohammad Jafar Emami; Farnaz Khademolhosseini

Volume 10, Issue 4 , December 2013, , Pages 229-237

Abstract
  Background: Primary malignant bone tumors are heterogeneous groups of neoplasms, which affect mainly children and adolescents. The most common types are Osteosarcoma, Ewing sarcoma and chondrosarcoma. Elevation of sCD30 and sCD40L has been observed in lymphoma, leukemia and autoimmune disorders. Objective: ...  Read More

CTLA4 Gene Variants in Autoimmunity and Cancer: a Comparative Review

Abbas Ghaderi

Volume 8, Issue 3 , September 2011, , Pages 127-149

Abstract
  Gene association studies are less appealing in cancer compared to autoimmune diseases. Complexity, heterogeneity, variation in histological types, age at onset, short survival, and acute versus chronic conditions are cancer related factors which are different from an organ specific autoimmune disease, ...  Read More

Listeria Monocytogenes Activated Dendritic Cell Based Vaccine for Prevention of Experimental Tumor in Mice

Masoumeh Khamisabadi; Samaneh Arab; Masoumeh Motamedi; Nematollah khansari; Seied Mohammad Moazzeni; Zahra Gheflati; Jamshid Hadjati

Volume 5, Issue 1 , March 2008, , Pages 36-44

Abstract
  Background: The use of dendritic cells (DCs) as a cellular adjuvant provides a promis-ing approach in immunotherapy of cancer. It has been demonstrated that Listeria mono-cytogenes activated DCs pulsed ex vivo with tumor antigens trigger a systemic Th1-biased specific immune response and a single dose ...  Read More

Dendritic Cells and Their Role in Cancer Immunotherapy

Ahmad Jalili

Volume 4, Issue 3 , December 2007, , Pages 127-144

Abstract
  Dendritic cells (DCs) are antigen presenting cells with unique capability to take up and process antigens in the peripheral blood and tissues. They subsequently migrate to draining lymph nodes where they present these antigens and stimulate naive T lympho-cytes. During their life cycle, DCs go through ...  Read More

Dendritic Cell Maturation with CpG for Tumor Immunotherapy

Samaneh Arab; Masoumeh Motamedi; Nematollah Khansari; Seied Mohammad Moazzeni; Zahra Gheflati; Jamshid Hadjati

Volume 3, Issue 3 , September 2006, , Pages 99-105

Abstract
  Background: Bacterial DNA has immunostimulatory effects on different types of immune cells such as dendritic cells (DCs). Application of DCs as a cellular adjuvant represents a promising approach in the immunotherapy of infectious disease and cancers. Objectives: To investigate the effect of tumor antigen ...  Read More

Monoclonal Antibodies as Therapeutic Agents: Advances and Challenges

Helmout Modjtahedi

Volume 2, Issue 1 , March 2005, , Pages 3-20

Abstract
  Despite the major advances in conventional forms of treatment (i.e. surgical techniques, radiotherapy and chemotherapy) and improved survival rates, cancer is still the second leading cause of death in developing countries. One major limitation of cytotoxic drugs and radiation in the treatment of cancer ...  Read More