Volume 21 (2024)
Volume 20 (2023)
Volume 19 (2022)
Volume 18 (2021)
Volume 17 (2020)
Volume 16 (2019)
Volume 15 (2018)
Volume 14 (2017)
Volume 13 (2016)
Volume 12 (2015)
Volume 11 (2014)
Volume 9 (2012)
Volume 8 (2011)
Volume 7 (2010)
Volume 6 (2009)
Volume 5 (2008)
Volume 4 (2007)
Volume 3 (2006)
Volume 2 (2005)
Volume 1 (2004)
Original Article
Detection of IL-20R1 and IL-20R2 mRNA in C57BL/6 Mice Astroglial Cells and Brain Cortex Following LPS Stimulation

Bahareh Abd Nikfarjam; Massoumeh Ebtekar; Farzaneh Sabouni; Zahra Pourpak; Maryam Kheirandish

Volume 10, Issue 2 , June 2013, Pages 62-69

Abstract
  Background: Astrocytes, which comprise ~90% of overall brain mass, are involved in brain immunity. These cells represent the non-professional class of CNS-resident APCs and may promote or inhibit CNS inflammation depending on the cytokines they secrete. IL-10 family of cytokines and their receptors, ...  Read More

Original Article
Long Acting Propranolol and HSP-70 Rich Tumor Lysate Reduce Tumor Growth and Enhance Immune Response against Fibrosarcoma in Balb/c Mice

Ahmad Khalili; Zuhair Muhammad Hassan; Shahram Shahabi; Ali Akbar Pourfathollah; Seyed Nasser Ostad; Shokoofe Noori; Mehdi Mahdavi; Habib Haybar; Ladan Langroudi

Volume 10, Issue 2 , June 2013, Pages 70-82

Abstract
  Background: Noradrenaline (NA), the principal neurotransmitter released from sympathetic nerve terminals, influences T-cell maturation, not only directly in developing T cells, but also indirectly, by acting on the thymic nonlymphoid cells. In vitro and in vivo studies have demonstrated the anti-proliferative, ...  Read More

Original Article
Interleukin-17 Serum Levels and TLR4 Polymorphisms in Ulcerative Colitis

Mojgan Mohammadi; Mohammad Javad Zahedi; Amin Reza Nikpoor; Mohammad Reza Baneshi; Mohammad Mahdi Hayatbakhsh

Volume 10, Issue 2 , June 2013, Pages 83-92

Abstract
  Background: Inflammatory bowel disease, an autoimmune disease, has two clinical manifestations including Crohn’s disease and ulcerative colitis (UC). IL-17 has been the target of intensive research in autoimmune diseases. The influence of Toll like receptor 4 (TLR-4) gene polymorphisms on IL-17 ...  Read More

Original Article
Hyperthermia Increases Natural Killer Cell Cytotoxicity against SW-872 Liposarcoma Cell Line

Shirin Farjadian; Marzie Norouzian; Vahid Younesi; Azin Ebrahimpour; Ramin Lotfi

Volume 10, Issue 2 , June 2013, Pages 93-102

Abstract
  Background: Although there is convincing data in support of the effectiveness of hyperthermia in tumor therapy, the molecular mechanisms underlying the clinical effects of hyperthermia are still poorly understood. Objective: To investigate natural killer (NK) cell cytotoxicity against heat-treated SW-872 ...  Read More

Original Article
MiR-143 Induces Expression of AIM2 and ASC in Jurkat Cell Line

Mohammad Momeni; Mohammad Reza Mirzaei; Nahid Zainodini; Gholamhossein Hassanshahi; Mohammad Kazemi Arababadi

Volume 10, Issue 2 , June 2013, Pages 103-109

Abstract
  Background: Absent in Melanoma 2 (AIM2) is an intracellular microbial dsDNA sensor which plays an important role in production of proinflammatory cytokines through Apoptosis associated Speck-like protein containing a Caspase activation and recruitment domain (ASC) and Caspase-1. Micro-RNAs (miRNAs) play ...  Read More

Original Article
Immunogenicity of a New Recombinant IpaC from Shigella dysenteriae Type I in Guinea Pig as a Vaccine Candidate

Fatemeh Malaei; Mahdi Hesaraki; Mojtaba Saadati; Ali Mohammad Ahdi; Mohammad Sadraeian; Hussein Honari; Shahram Nazarian

Volume 10, Issue 2 , June 2013, Pages 110-117

Abstract
  Background: Recombinant vaccine technology is one of the most developed means in controlling infectious diseases. However, an effective vaccine against Shigella is still missing. Objective: To evaluate recombinant IpaC protein of Shigella as a vaccine candidate. Methods: In this study we cloned IpaC ...  Read More

Original Article
Immune Deviation in Recurrent Vulvovaginal Candidiasis: Correlation with Iron Deficiency Anemia

Nadereh Naderi; Zahra Etaati; Mansoreh Rezvani Joibari; Seyed Alireza Sobhani; Said Hosseni Tashnizi

Volume 10, Issue 2 , June 2013, Pages 118-126

Abstract
  Background: Iron Deficiency Anemia (IDA) has been controversially linked to IL-4 production in previous studies. A predominant Th1 response leads to resistance against recurrent vulvovaginal candidiasis (RVVC), whereas a Th2 response exacerbates the disease. Objective: To investigate the possible effect ...  Read More