Volume 19 (2022)
Volume 18 (2021)
Volume 17 (2020)
Volume 16 (2019)
Volume 15 (2018)
Volume 14 (2017)
Volume 13 (2016)
Volume 12 (2015)
Volume 11 (2014)
Volume 10 (2013)
Volume 9 (2012)
Volume 8 (2011)
Volume 7 (2010)
Volume 6 (2009)
Volume 5 (2008)
Volume 4 (2007)
Volume 3 (2006)
Volume 2 (2005)
Volume 1 (2004)
1. Evaluation of the Relationship between Pro-Inflammatory Cytokine Levels and Clinical Findings of Fibromyalgia Syndrome

Pınar Ellergezen; Alev ALP; Sinan Çavun

Volume 18, Issue 4 , December 2021, , Pages 338-345


  Background: Immune system has an important effect on pain-related disorders such as fibromyalgia syndrome (FMS). There is no specific laboratory technique for the diagnosis of FMS, but measuring serum proinflammatory cytokines may help. Objective: The purpose of our study was to determine the serum levels ...  Read More

3. IL-6 and IL-10 Closely Correlate with Bacterial Bloodstream Infection

Jingjing Guan; Zhongyong Wang; Xiaoyuan Liu; Yujie Jiang; Qiuqi Gao; Qing Wu; Hong Lu; Lianfeng Wu; Zhuo Zhang; Xiangyang Lin; Jingjing Qian

Volume 17, Issue 3 , September 2020, , Pages 185-203


  Background: Given the high mortality of bacterial bloodstream infections (BSI), blood culture results do not meet clinical needs timely due to being time-consuming and having low positive rate. Whether we can identify the severity and type of bacterial infections by cytokines is a controversial issue. ...  Read More

5. Serum and Peritoneal Fluid Cytokine Profiles in Infertile Women with Endometriosis

Majid Tarokh; Marefat Ghaffari Novin; Tahereh Poordast; Zohreh Tavana; Hamid Nazarian; Mohsen Norouzian; Behrouz Gharesi-Fard

Volume 16, Issue 2 , June 2019, , Pages 151-162


  Background: Endometriosis is a chronic inflammatory disease with the growth of endometrial cells out of uterus and in the peritoneal cavity. T cell subsets participate in the establishment and progress of the disease by producing different cytokines. Objective: To investigate a group of cytokines related ...  Read More

6. IL-6/IL-10 Ratio as A Prognostic and Predictive Marker of the Severity of Inherited Epidermolysis Bullosa

Marilina Tampoia; Letizia Abbracciavento; Marella Morrone; Ruggiero Fumarulo

Volume 14, Issue 4 , December 2017, , Pages 340-349

  Background: Recent studies have shown that cytokines have an important role in the pathogenesis of inflammatory diseases and can be used as prognostic markers. Objective: To evaluate the IL-6/IL-10 ratio in patients with Inherited Epidermolysis Bullosa (EB) as a prognostic marker. Methods: Serum levels ...  Read More

7. Reduced IFN-γ Production in Chronic Brucellosis Patients

Ehsanollah Ghaznavi-Rad; Khadijeh Khosravi; Nader Zarinfar; Ghasem Mosayebi

Volume 14, Issue 3 , September 2017, , Pages 215-222

  Background: Brucella is a well-known intracellular bacterium entailing acute and chronic illnesses in humans and domestic animals. The infection chronicity may be affected by the cell-mediated immunity and cytokine patterns. Objective: To evaluate the patterns of T-helper cytokines in patients suffering ...  Read More

8. Low 17β-estradiol Levels Are Better Inducers of Regulatory Conditioned T Cells In-Vitro

Ramina Fatemi; Ebrahim Mirzadegan; Zohreh Vahedian; Amir Hassan Zarnani; Mahmood Jeddi-Tehrani; Farah Idali

Volume 14, Issue 2 , June 2017, , Pages 159-171

  Background: 17β-estradiol (E2) has been known to modulate immune response. Recent studies indicate that E2 at pregnancy level plays a role in regulating T cell response. Objective: To investigate the optimum dose of E2 (from 10-9 to 10-7 M) in mediating the generation of regulatory T cells (Tregs), ...  Read More

9. Whole Tumor Cell Vaccine Adjuvants: Comparing IL-12 to IL-2 and IL-15

Abdolkarim Sheikhi; Abdollah Jafarzadeh; Parviz Kokhaei; Mohammad Hojjat-Farsangi

Volume 13, Issue 3 , September 2016, , Pages 148-166

  Cancer immunotherapy (passive or active) involves treatments which promote the ability of the immune system to fight tumor cells. Several types of immunotherapeutic agents, such as monoclonal antibodies, immune checkpoint inhibitors, non-specific immunomodulatory agents, and cancer vaccines are currently ...  Read More

10. Altered Serum Cytokine Profiles in Relapse Phase of Relapsing-Remitting Multiple Sclerosis

Forooz Peiravian; Hamid Rajaian; Afshin Samiei; Nasser Gholijani; Behrouz Gharesi-Fard; Pooneh Mokaram; Abbas Rahimi-Jaberi; Eskandar Kamali Sarvestani

Volume 13, Issue 3 , September 2016, , Pages 186-196

  Background: Multiple sclerosis (MS) is a demyelinating disease of the central nervous system and cytokines may play a role in the development of MS lesions. Objective: To determine levels of different cytokines in patients with relapsing-remitting MS (RR-MS) compared to healthy controls. Methods: Profiles ...  Read More

11. The Immunostimulatory Effect of Lactic Acid Bacteria in a Rat Model

Murat Karamese; Hakan Aydin; Emin Sengul; Volkan Gelen; Cigdem Sevim; Duran Ustek; Emre Karakus

Volume 13, Issue 3 , September 2016, , Pages 220-228

  Background: Probiotics are “live”, beneficial microbes that provide important health benefits in their hosts. There is significant interest in the modulation and regulation of the immune function by probiotics. Objective: To investigate the immunomodulatory effects of a probiotic mixture, ...  Read More

12. Interferon β-1a and Atorvastatin in the Treatment of Multiple Sclerosis

Keyvan Ghasami; Fardin Faraji; Masoud Fazeli; Ali Ghazavi; Ghasem Mosayebi

Volume 13, Issue 1 , March 2016, , Pages 16-26

  Background: Statins, widely used cholesterol-lowering agents, have also been demonstrated to have anti-inflammatory and immunomdulatory effects. Objective: To evaluate the effects of atorvastatin in combination with Interferon-β in the treatment of multiple sclerosis (MS) in a randomized controlled ...  Read More

13. Inhibition of Nitric Oxide Production and Proinflammatory Cytokines by Several Medicinal Plants

Zahra Amirghofran; Saeed Malek-Hosseini; Hossein Golmoghaddam; Fathollah Kalantar; Mehdi Shabani

Volume 8, Issue 3 , September 2011, , Pages 159-169

  Background: A number of medicinal plants have been used to treat various immunological diseases. Nitric oxide (NO) has an important regulatory role in the various types of inflammatory processes. Objective: To investigate the NO modulatory activity of the extracts of several medicinal plants native to ...  Read More

14. Serum Cytokines Profiles in Iranian Patients with Preeclampsia

Reza Mansouri; Firoozeh Akbari; Mohammad Vodjgani; Fereidoun Mahboudi; Fathollah Kalantar; Mahroo Mirahmadian

Volume 4, Issue 3 , December 2007, , Pages 179-185

  Background: Preeclampsia is a major cause of mortality and morbidity and is also a leading cause of preterm birth and intrauterine growth retardation. Several studies have reported abnormal levels of cytokines in women with preeclampsia. Objectives: To detect serum levels of various cytokines in pregnant ...  Read More

15. Cytokine Production in Hymenolepis Nana Infection

Aboulghasem Ajami; Alireza Rafiei

Volume 4, Issue 4 , December 2007, , Pages 236-240

  Background: Although many experimental studies provide convincing evidence that type II immunity is protective against helminths, recent data in mice demonstrate that Th1 is also impor-tant in some cestodes like Hymenolepis nana. Objective: To identify the role of Th1 and Th2 lymphocytes in immunity ...  Read More

16. Assessment of the Immune System Activity in Iranian Patients with Major Depression Disorder (MDD)

Reza Farid Hosseini; Farahzad Jabbari Azad; Ali Talaee; Sara Miri; Naghme Mokhber; Farhad Farid Hosseini; Habibollah Esmaeili; Mahmoud Mahmoudi; Hoshang Rafatpanah; Mohammadreza Mohammadi

Volume 4, Issue 1 , March 2007, , Pages 38-43

  Background: Major Depression Disorder (MDD) is a common disorder with preva-lence of 15% among men and up to 25% among women. In recent years the association of immune system alterations and MDD has been investigated. Assessments of immu-nologic and inflammatory responses in these patients enhance our ...  Read More