Volume 20 (2023)
Volume 19 (2022)
Volume 18 (2021)
Volume 17 (2020)
Volume 16 (2019)
Volume 15 (2018)
Volume 14 (2017)
Volume 13 (2016)
Volume 12 (2015)
Volume 11 (2014)
Volume 10 (2013)
Volume 9 (2012)
Volume 8 (2011)
Volume 7 (2010)
Volume 6 (2009)
Volume 5 (2008)
Volume 4 (2007)
Volume 3 (2006)
Volume 2 (2005)
Volume 1 (2004)
Anti-inflammatory Mechanisms of IL-38 in Chinese Patients with Allergic Rhinitis

Xiaoqiang Wang; Yang Shen; Xia Ke; Suling Hong

Volume 20, Issue 1 , March 2023, , Pages 92-103


  Background: T-helper 17 (Th17) cell response is engaged in the onset of allergic rhinitis (AR). Moreover, interleukin (IL)-38 is thought to be involved in inhibiting cytokine secretion in the Th17 pathway.Objective: To evaluate the regulatory function of IL-38 on abnormal Th17 responses in Chinese patients ...  Read More

Predictive Value of the Serum Diamine Oxidase Level in the Diagnosis of Seasonal Allergic Rhinitis

Ali Aghili; Ahmad Rezaeian

Volume 19, Issue 4 , December 2022, , Pages 395-403


  Background: Allergic rhinitis (AR) is characterized by the increased sensitivity of the nasal mucosa to allergens and has a significant impact on life quality. There is promising evidence that biomarkers can help in the diagnosis, treatment, and follow-up of patients with AR. Diamine oxidase (DAO) ...  Read More

The Regulation of the IL-18 on Group 2 Innate Lymphoid Cells in Allergic Rhinitis

Chuling Li; Yaxiong Xu; Xianglin Luo; Fajian Chen

Volume 18, Issue 3 , September 2021, , Pages 188-194


  Background: Group 2 innate lymphoid cells (ILC2s) promote allergic inflammation by producing interleukin-4 (IL-4), IL-5, IL-9, and IL-13. IL-18 can promote T helper 2 cell (Th2) response by inducing IL-4, and IL-13 production from mast cells and basophils. However, the regulation of IL-18 on ILC2s remained ...  Read More

Interleukin-27 Suppresses T Helper-17 Inflammation in Allergic Rhinitis

Hong Ouyang; Jie Cheng; Jingdong Du; Huiyun Gan; Zheng Lu

Volume 17, Issue 4 , December 2020, , Pages 275-282


  Background: T helper 17 (Th17) cells and the related cytokines, interleukin (IL)- 17 and IL-23, were proved to play pivotal roles during the development of allergic rhinitis (AR). IL-27, an anti-inflammatory cytokine, has been reported to promote the production of IL-12R and induce Th1 cell responses. ...  Read More

Clinical Efficacy of Vitamin D3 Adjuvant Therapy in Allergic Rhinitis: A Randomized Controlled Trial

Xiaoling Liu; Xiaojia Liu; Yu Ren; Hongxin Yang; Xiaolei Sun; Haiyun Huang

Volume 17, Issue 4 , December 2020, , Pages 283-291


  Background: Vitamin D supplementation has been proven to be effective in the treatment of allergic rhinitis (AR). Objective: We conducted the present study to explore the role and efficacy of vitamin D adjuvant therapy for the treatment of inflammation in patients with AR. Methods: Out of 127 patients ...  Read More

H2-EB1 Molecule Alleviates Allergic Rhinitis Symptoms of H2-Eb1 Knockout Mice

Linge Li; Bin Hu; Juan Feng; Yu Zhang; Xi Shou; Yu Tian; Chunrong Jiang; Hua Zhang

Volume 12, Issue 4 , December 2015, , Pages 263-273

  Background:   H2-EB1 molecule which is the homolog of Human HLA-DRB1 is proposed to be associated with allergic rhinitis (AR). Construction of   H2-Eb1 knockout animal models provides a tool to elucidate the role of H2-EB1 and AR pathogenesis. Objective:   To establish the H2-Eb1 knockout ...  Read More

Association of Haptoglobin Phenotypes with Serum Levels of IgE and IgA in Allergic Rhinitis Patients

Hossein Ali Khazaei; Alireza Nakhaei; Golam Ali Dashti; Mehdi Mohammadi; Fariba Hejazenia; Noura Mehrangeez; Amin Khazaei

Volume 9, Issue 4 , December 2012, , Pages 254-260

  Background: Allergic rhinitis (AR) is an allergic disorder of the nasal tissue that underlies diseases such as sinusitis, otits and asthma. Different predisposing factors including immunological and non-immunological factors contribute to the disease pathogenesis. Objective: To investigate association ...  Read More

FOXP3 and TGF-β Gene Polymorphisms in Allergic Rhinitis

Haddi Hassannia; Saeid Abediankenari; Javad Ghaffari

Volume 8, Issue 4 , December 2011, , Pages 218-225

  Background: Regulatory CD4+T (Treg) cells are effective in maintaining immune tolerance. Objective: To investigate single nucleotide polymorphisms (SNPs) of Transforming Growth Factor β-1 (TGF-β1) and Forkhead Box Protein 3 (FOXP3) genes in Iranian patients with allergic rhinitis (AR). Methods: ...  Read More

Hypersensitivity to House Dust Mite and Cockroach Is the Most Common Allergy in North of Iran

Javad Ghaffari; Mohammad KHademloo; Mohammadjafar Saffar; Alireza Rafiei; Farzad Masiha

Volume 7, Issue 4 , December 2010, , Pages 234-239

  Background: Asthma and allergic rhinitis are among the most common diseases in the world. Objective: The aim of this study was to detect, by skin prick test, aeroallergens in allergic patients in Sari, Mazandaran in north of Iran. Methods: This is a prospective study of skin prick test of aeroallergens ...  Read More

The Prevalence of Allergic Rhinitis among 11-15 Years-old Children in Shiraz

Hedaiat Akbari; Reza Farid-Hosseini; Sara Miri; Reza Amin

Volume 1, Issue 2 , September 2004, , Pages 133-137

  Background: Allergic rhinitis is one of the most common forms of allergic disorders affecting children. The prevalence rate of allergic rhinitis differs among countries and even among regions within the same country.   Objectives: To determine the prevalence of childhood allergic rhinitis and the ...  Read More

Serum Level of Selenium, IL-4, IL-10 & IFN-g in Patients with Allergic Asthma, Allergic Rhinitis and Healthy Controls

Reza Farid; Farahzad Jabbari Azad; Javad Gaffari; Alireza Rangbar; Zahra Nikjoy

Volume 1, Issue 1 , June 2004, , Pages 71-75

  Background: Allergic diseases have increased during the past decade worldwide. Th2 type lymphocyte response is known to play an important role in the process of allergic inflammation. IL-4, a mediator of type II cytokine response increases IgE synthesis and Interferon gamma, a cytokine of type I response ...  Read More