Volume 18 (2021)
Volume 17 (2020)
Volume 16 (2019)
Volume 15 (2018)
Volume 14 (2017)
Volume 12 (2015)
Volume 11 (2014)
Volume 10 (2013)
Volume 9 (2012)
Volume 8 (2011)
Volume 7 (2010)
Volume 6 (2009)
Volume 5 (2008)
Volume 4 (2007)
Volume 3 (2006)
Volume 2 (2005)
Volume 1 (2004)
Original Article
1. CD8+ T Lymphocyte Subsets in Bladder Tumor Draining Lymph Nodes

Zahra Faghih; Saeideh Sadat Shobeiri; Ali Ariafar; Mohsen Sarkarian; Shahryar Zeighami; Nazanin Nazari; Saeed Abbasi-Sarvak; Nasrollah Erfani

Volume 13, Issue 4 , Autumn 2016, Pages 237-248

  Background: Cytotoxic CD8+ T cells, as essential parts of the adaptive immune system, play pivotal roles in anti-tumor immune responses. It is well documented that cytokine expression profiles and activation status of these cells during anti-tumor immune responses affect the outcome of host-tumor ...  Read More

Original Article
2. Resting and Activated Natural Tregs Decrease in the Peripheral Blood of Patients with Atherosclerosis

Mohammadreza Yazdani; Shahdad Khosropanah; Ahmad Hosseini; Mehrnoosh Doroudchi

Volume 13, Issue 4 , Autumn 2016, Pages 249-262

  Background: Atherosclerosis is a chronic inflammatory disease affecting large and medium arteries. CD4+ T cells are known to play a role in the progression of the disease. CD4+CD25+Foxp3+ natural Treg (nTreg) cells seem to have a protective role in the disease and their reduction in acute coronary ...  Read More

Original Article
3. The Effect of Safranal on Th1/Th2 Cytokine Balance

Reza Feyzi; Mohammad Hossein Boskabady; Seyedeh Masoumeh Seyed hosseini Tamijani; Houshang Rafatpanah; Seyed Abdolrahim Rezaei

Volume 13, Issue 4 , Autumn 2016, Pages 263-273

  Background: Several biological and medical benefits of Saffron, Crocus sativus (Iridaceae), have been demonstrated. However, mechanisms of actions for purified constituents are greatly unknown. Objective: To examine the effects of Safranal, a main constituent of Saffron stigma, on cell viability and ...  Read More

Original Article
4. Effect of Mesenchymal Stem Cells on ILT3 Expression in the Splenocytes of Skin Graft Recipient Mice

Ali Moravej; Mohammad-Hossein Karimi; Bita Geramizadeh; Mahdokht Hossein Aghdaie; Omid Kohi-Hoseinabadi; Salimeh Ebrahimnezhad

Volume 13, Issue 4 , Autumn 2016, Pages 274-288

  Background: Mesenchymal stem cells (MSCs) are considered as effective therapeutic cells in transplantation due to their immunomodulatory activities. However, precise mechanism of MSCs immunomodulatory activity is not completely understood. Objectives: To study the role of Immunoglobulin-like transcripts-3 ...  Read More

Original Article
5. Immunogenicity of a DNA Vaccine Encoding Ag85a-Tb10.4 Antigens from Mycobacterium Tuberculosis

Zahra Meshkat; Amir Teimourpour; Samira Rashidian; Mohsen Arzanlou; Roghayeh Teimourpour

Volume 13, Issue 4 , Autumn 2016, Pages 289-295

  Background: Tuberculosis is a life threatening disease that is partially prevented by BCG vaccine. Development of more effective vaccines is an urgent priority in TB control. Ag85a and Tb10.4 are the members of culture filter protein (CFP) of M. tuberculosis that have high immunogenicity. Objective: ...  Read More

Original Article
6. The Expression of T-Helper Associated Transcription Factors and Cytokine Genes in Pre-Eclampsia

Behrouz Gharesi-Fard; Fatemeh Mobasher-Nejad; Fatemeh Nasri

Volume 13, Issue 4 , Autumn 2016, Pages 296-308

  Background: Pre-eclampsia (PE) is known as a main factor contributing to fetomaternal mortality, which might affect 2-8% of all pregnancies after the twentieth week of gestation. The balance of T helper subsets is essential to sustain a normal pregnancy and preventing fetomaternal complications. Objective: ...  Read More

Original Article
7. Tumor Necrosis Factor-α and Interleukin-1- β Polymorphisms in Pre-Eclampsia

Zeinab Tavakkol Afshari; Hamid Reza Rahimi; Seyed Morteza Ehteshamfar; Rashin Ganjali; Fatemeh Tara; Abbas Shapouri Moghadam

Volume 13, Issue 4 , Autumn 2016, Pages 309-316

  Background: Pre-eclampsia is the most common critical condition during pregnancy. Plasma concentrations of tumor necrosis factor-alpha (TNF-α) and interleukin-1-beta (IL-1β) increase in pregnant women with pre-eclampsia, compared to normal pregnant women. Objective: To investigate the polymorphisms ...  Read More

Short Paper
8. Serum Levels of IL-10 and IL-22 Cytokines in Patients with Psoriasis

Mohammad Reza Sobhan; Mahmood Farshchian; Ali Hoseinzadeh; Hamid Reza Ghasemibasir; Ghasem Solgi

Volume 13, Issue 4 , Autumn 2016, Pages 317-323

  Background: As a chronic inflammatory condition, psoriasis results from an interaction between genetic and immunologic factors in a predisposing environment. In spite of compelling evidence for the role of T cells and cytokines in psoriasis, interleukin (IL)- 10 and IL-22 have not been sufficiently ...  Read More