Volume 21 (2024)
Volume 20 (2023)
Volume 19 (2022)
Volume 18 (2021)
Volume 17 (2020)
Volume 16 (2019)
Volume 15 (2018)
Volume 14 (2017)
Volume 12 (2015)
Volume 11 (2014)
Volume 10 (2013)
Volume 9 (2012)
Volume 8 (2011)
Volume 7 (2010)
Volume 6 (2009)
Volume 5 (2008)
Volume 4 (2007)
Volume 3 (2006)
Volume 2 (2005)
Volume 1 (2004)
Review Article
Whole Tumor Cell Vaccine Adjuvants: Comparing IL-12 to IL-2 and IL-15

Abdolkarim Sheikhi; Abdollah Jafarzadeh; Parviz Kokhaei; Mohammad Hojjat-Farsangi

Volume 13, Issue 3 , September 2016, Pages 148-166

Abstract
  Cancer immunotherapy (passive or active) involves treatments which promote the ability of the immune system to fight tumor cells. Several types of immunotherapeutic agents, such as monoclonal antibodies, immune checkpoint inhibitors, non-specific immunomodulatory agents, and cancer vaccines are currently ...  Read More

Original Article
Regulatory T Cells and Myeloid-Derived Suppressor Cells in Patients with Peptic Ulcer and Gastric Cancer

Hamideh Mesali; Abolghasem Ajami; Hadi Hussein-Nattaj; Alireza Rafiei; Zeinab Rajabian; Hossein Asgarian-Omran; Vahid Hosseini; Tarang Taghvaei; Mohsen Tehrani

Volume 13, Issue 3 , September 2016, Pages 167-177

Abstract
  Background: Regulatory T Cells (Tregs) and Myeloid-Derived Suppressor Cells (MDSCs) are two main regulatory cells modulating the immune responses in inflammation and cancer. Objective: To investigate and compare Tregs and MDSCs in peptic ulcer and gastric cancer. Methods: Patients with dyspepsia were ...  Read More

Original Article
Natural Killer Cell Cytotoxicity Against SKOV3 after HLA-G Downregulation by shRNA

Nazanin Nazari; Shirin Farjadian

Volume 13, Issue 3 , September 2016, Pages 178-185

Abstract
  Background: HLA-G is a nonclassical HLA class I molecule which, when elevated in tumor cells, is one of the main factors involved in tumor evasion of immune responses including NK and T cells. Objective: To evaluate the effect of HLA-G downregulation on NK cell cytotoxicity in tumor cell lines. Methods: ...  Read More

Original Article
Altered Serum Cytokine Profiles in Relapse Phase of Relapsing-Remitting Multiple Sclerosis

Forooz Peiravian; Hamid Rajaian; Afshin Samiei; Nasser Gholijani; Behrouz Gharesi-Fard; Pooneh Mokaram; Abbas Rahimi-Jaberi; Eskandar Kamali Sarvestani

Volume 13, Issue 3 , September 2016, Pages 186-196

Abstract
  Background: Multiple sclerosis (MS) is a demyelinating disease of the central nervous system and cytokines may play a role in the development of MS lesions. Objective: To determine levels of different cytokines in patients with relapsing-remitting MS (RR-MS) compared to healthy controls. Methods: Profiles ...  Read More

Original Article
Effect of TNF-α Blockade in Gingival Crevicular Fluid on Periodontal Condition of Patients with Rheumatoid Arthritis

Zeinab Kadkhoda; Aliakbar Amirzargar; Zahra Esmaili; Mahdi Vojdanian; Solmaz Akbari

Volume 13, Issue 3 , September 2016, Pages 197-203

Abstract
  Background: Periodontitis and rheumatoid arthritis (RA) share a number of clinical and pathologic features, one of which is the presence of the tumor necrosis factor alpha (TNF-α)-induced bone resorption that is involved in the pathogenesis of both. Objectives: To investigate the effect of TNF-α ...  Read More

Original Article
Immunogenicity of 23-Valent Pneumococcal Vaccine in Children with Systemic Lupus Erythematosus

Soheila Alyasin; Marzieh Adab; Asieh Hosseinpour; Reza Amin; Maryam Babaei

Volume 13, Issue 3 , September 2016, Pages 204-219

Abstract
  Background: Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease which is characterized by B-cell abnormality and auto-antibody generation. Since bacterial infections are the most important causes of mortality in these patients, pneumococcal vaccination is recommended for children with ...  Read More

Original Article
The Immunostimulatory Effect of Lactic Acid Bacteria in a Rat Model

Murat Karamese; Hakan Aydin; Emin Sengul; Volkan Gelen; Cigdem Sevim; Duran Ustek; Emre Karakus

Volume 13, Issue 3 , September 2016, Pages 220-228

Abstract
  Background: Probiotics are “live”, beneficial microbes that provide important health benefits in their hosts. There is significant interest in the modulation and regulation of the immune function by probiotics. Objective: To investigate the immunomodulatory effects of a probiotic mixture, ...  Read More

Short Paper
Maternal Serum and Cervicovaginal IL-6 in Patients with Symptoms of Preterm Labor

Parisa Yavari Kia; Behzad Baradaran; Mahnaz Shahnazi; Mohammad Asghari Jafarabadi; Vahid Khaze; Shakiba Pourasad Shahrak

Volume 13, Issue 3 , September 2016, Pages 229-236

Abstract
  Background: Preterm birth is a common problem in obstetrics. Objective: To measure maternal serum interlukin-6 in mothers with preterm uterine contractions and compare it with cervicovaginal interlukin-6 in the same women. Methods: In this cross-sectional study, we measured interlukin-6 in the sera and ...  Read More