Volume 19 (2022)
Volume 18 (2021)
Volume 17 (2020)
Volume 16 (2019)
Volume 15 (2018)
Volume 14 (2017)
Volume 13 (2016)
Volume 12 (2015)
Volume 11 (2014)
Volume 10 (2013)
Volume 9 (2012)
Volume 7 (2010)
Volume 6 (2009)
Volume 5 (2008)
Volume 4 (2007)
Volume 3 (2006)
Volume 2 (2005)
Volume 1 (2004)
Review Article
1. CTLA4 Gene Variants in Autoimmunity and Cancer: a Comparative Review

Abbas Ghaderi

Volume 8, Issue 3 , Summer 2011, Pages 127-149

  Gene association studies are less appealing in cancer compared to autoimmune diseases. Complexity, heterogeneity, variation in histological types, age at onset, short survival, and acute versus chronic conditions are cancer related factors which are different from an organ specific autoimmune disease, ...  Read More

Original Article
2. Validation of a β-ME ELISA for Detection of Anti Leishmania donovani Antibodies in Eastern Sudan

Elfadil Abass; Abdelhafeiz Mahamoud; Durria Mansur; Mehdi Mohebali; Abdollah el Harith

Volume 8, Issue 3 , Summer 2011, Pages 150-158

  Background: A β-mercaptoethnol (β-ME)-treated promastigote antigen of L. donovani was successfully employed in direct agglutination test (DAT) for the diagnosis of visceral leishmaniasis (VL). Objective: The β-ME-treated antigen was further incorporated into an enzyme-linked immunosorbent ...  Read More

Original Article
3. Inhibition of Nitric Oxide Production and Proinflammatory Cytokines by Several Medicinal Plants

Zahra Amirghofran; Saeed Malek-Hosseini; Hossein Golmoghaddam; Fathollah Kalantar; Mehdi Shabani

Volume 8, Issue 3 , Summer 2011, Pages 159-169

  Background: A number of medicinal plants have been used to treat various immunological diseases. Nitric oxide (NO) has an important regulatory role in the various types of inflammatory processes. Objective: To investigate the NO modulatory activity of the extracts of several medicinal plants native to ...  Read More

Original Article
4. Detection of IL-4, IL-6 and IL-12 Serum Levels in Generalized Aggressive Periodontitis

Maryam Robati; Ardeshir Ranjbari; Mehri Ghafourian Boroujerdnia; Zahra Chinipardaz

Volume 8, Issue 3 , Summer 2011, Pages 170-175

  Background: Periodontitis is a multifactorial chronic inflammatory disease characterized by destruction of tooth-supporting tissues. Environmental and genetic factors as well as the immune system participate in this process. Recent studies have attempted to elucidate the role of cytokine networks involved ...  Read More

Original Article
5. Effect of Ibuprofen on IL-1β, TNF-α and PGE2 Levels in Periapical Exudates: A Double Blinded Clinical Trial

Shahriar Shahriari; Aliasghar Rezaei; Seyed Mohsen Jalazadeh; Khosro Mani; Alireza Zamani

Volume 8, Issue 3 , Summer 2011, Pages 176-182

  Background: Bone resorption is one of the main features of inflammatory periapical lesions and is mainly mediated by interleukin-1 beta (IL-1β), tumor necrosis factoralpha (TNF-α) and prostaglandin-E2 (PGE2). Recent investigations of these lesions revealed that pharmacological modulation may ...  Read More

Original Article
6. Serum Interleukin-23 Levels in Patients with Ulcerative Colitis

Mojgan Mohammadi; Mohammad Mahdi Hayatbakhsh; Mohammad Javad Zahedi; Mohammad Reza Jalalpour; Amin Pakgohar

Volume 8, Issue 3 , Summer 2011, Pages 183-188

  Background: Patients with ulcerative colitis are at increased risk of inflammation. Interleukin 23 (IL-23) is a newly identified cytokine with increased expression in inflamed biopsies of colon mucosa in patients with Crohn's disease; however, there is inconsistent evidence on its role in ulcerative ...  Read More

Short Paper
7. Auto-antibodies in Patients with Inflammatory Bowel Disease Unclassified

Batool Mutar Mahdi

Volume 8, Issue 3 , Summer 2011, Pages 189-194

  Background: Inflammatory bowel disease unclassified (IBDU) is considered to be an aberrant immune response with loss of tolerance to many antigens. Objective: This paper tries to address whether there is any value to test for auto-antibodies in such patients. Methods: 60 patients with inflammatory bowel ...  Read More