Volume 18 (2021)
Volume 17 (2020)
Volume 16 (2019)
Volume 15 (2018)
Volume 14 (2017)
Volume 13 (2016)
Volume 12 (2015)
Volume 11 (2014)
Volume 10 (2013)
Volume 8 (2011)
Volume 7 (2010)
Volume 6 (2009)
Volume 5 (2008)
Volume 4 (2007)
Volume 3 (2006)
Volume 2 (2005)
Volume 1 (2004)
Review Article
1. Revisiting Beta 2 Glycoprotein I, the Major Autoantigen in the Antiphospholipid Syndrome

Soheila Rahgozar

Volume 9, Issue 2 , Spring 2012, Pages 73-85

  Beta 2 glycoprotein I (β2GPI) is a single chain 50 kDa highly glycosylated glycoprotein at an approximate concentration of 4 μM in cells. The abundance of this protein in plasma and its high state of preservation indicate the important role of this protein in mammalian. In addition, β2GPI ...  Read More

Original Article
2. Immune Responses against a New HIV-1 p24-gp41/pCAGGS-IL-12 DNA Vaccine in Balb/c Mice

Fatemeh Roodbari; Farzaneh Sabahi; Mohamad Nabi Sarbolouki; Farzaneh Barkhordari; Ahmad Adeli; Amel Jamedar; Fereidoun Mahboudi

Volume 9, Issue 2 , Spring 2012, Pages 86-97

  Background: Development of an effective vaccine is highly needed in order to restrict the AIDS pandemic. DNA vaccines initiate both arms of immunity without the potential of causing disease. HIV-1 p24 and gp41 (gag and env) proteins play important roles in viral pathogenesis and are effective candidates ...  Read More

Original Article
3. Phenotypic and Functional Comparison between Flask Adherent and Magnetic Activated Cell Sorted Monocytes Derived Dendritic Cells

Nowruz Delirezh; Ehsan Shojaeefar

Volume 9, Issue 2 , Spring 2012, Pages 98-108

  Background: Generation of an effective dendritic cell (DC) based cancer vaccine depends on appropriate differentiation of monocytes in vitro. Objective: To compare the effects of monocyte separation methods, flask adherence (Flask-DC) and magnetic activated cell sorting (MACS-DC), on phenotypic and functional ...  Read More

Original Article
4. Natural Oils Enhance IL-10 and IFN-γ Production by Human PBMCs Cultured with Malassezia furfur

Mohammad Ali Rezaee; Yousef Motaharinia; Werya Hosseini; Ali Jalili; Ahmad Rashidi; Bita Mosavi; Ghasem Zamini; Mohammad Reza Rahmani

Volume 9, Issue 2 , Spring 2012, Pages 109-118

  Background: Malassezia furfur is alipophilic yeast that causes skin disease. Objective: To evaluate the level of IL-10, IFN-γ and IL-12P70 in co-incubation of M. furfur grown on different forms of natural oils with PBMCs of healthy individuals. Methods: PBMCs were obtained from blood samples of ...  Read More

Original Article
5. Genistein Induces a Protective Immunomodulatory Effect in a Mouse Model of Cervical Cancer

Ali Ghasemi; Hoorieh Soleimanjahi; Soodeh Razeghi; Ali Gorji; Alijan Tabaraei; Abdolvahab Moradi; Akram Alizadeh; Mohammad Ali Vakili

Volume 9, Issue 2 , Spring 2012, Pages 119-127

  Background: Genistein (GEN), a naturally occurring flavonoid present in soy bean, has attracted scientific interest for its possible benefits in cancer. Objective: The potential immunomodulatory effects of genistein on the immune system and against TC-1 tumor cell line were evaluated in adult female ...  Read More

Original Article
6. IL-23 Receptor Gene rs7517847 and rs1004819 SNPs in Ulcerative Colitis

Mohammad Mahdi Hayatbakhsh; Mohammad Javad Zahedi; Mohsen Shafiepour; Amin Reza Nikpoor; Mojgan Mohammadi

Volume 9, Issue 2 , Spring 2012, Pages 128-135

  Background: Crohn’s disease (CD) and ulcerative colitis (UC) are two major clinical presentations of inflammatory bowel disease (IBD). Many novel candidate genes have been found to be associated with increased risk for IBD. Recently IL-23 receptor gene is identified as an IBD associated gene in ...  Read More

Original Article
7. Comparison of Intravitreal Injection of Bevacizumab and Triamcinolone Acetonide in the Treatment of Uveitic Macular Edema

Mansour Rahimi; Seyed Sahabaldin Shahrzad; Mohammad Banifatemi

Volume 9, Issue 2 , Spring 2012, Pages 136-144

  Background: Cystoid Macular Edema (CME) is one of the most common and sight threatening complications of uveitis. Intravitreal injection of corticosteroids and anti-VEGF antibody are two routine options for treatment. Objective: To compare the effects of intravitreal injections of Bevacizumab and Triamcinolone ...  Read More