Volume 19 (2022)
Volume 18 (2021)
Volume 17 (2020)
Volume 16 (2019)
Volume 15 (2018)
Volume 13 (2016)
Volume 12 (2015)
Volume 11 (2014)
Volume 10 (2013)
Volume 9 (2012)
Volume 8 (2011)
Volume 7 (2010)
Volume 6 (2009)
Volume 5 (2008)
Volume 4 (2007)
Volume 3 (2006)
Volume 2 (2005)
Volume 1 (2004)
Original Article
1. CD4+ T Cells are Exhausted and Show Functional Defects in Chronic Lymphocytic Leukemia

Esmaeil Allahmoradi; Saeid Taghiloo; Mohsen Tehrani; Hadi Hossein-Nattaj; Ghasem Janbabaei; Ramin Shekarriz; Hossein Asgarian-Omran

Volume 14, Issue 4 , Autumn 2017, Pages 257-269

  Background: Chronic lymphocytic leukemia (CLL) is the most common adult leukemia in the western world. This health problem is caused due to the accumulation of mature B-lymphocytes in the peripheral blood and bone marrow. In the course of cancer, CD4+ T cells become “exhausted” and characterized ...  Read More

Original Article
2. CD40 Knocked Down Tolerogenic Dendritic Cells Decrease Diabetic Injury

Aziz Mahmoudzadeh; Ali Akbar Pourfathollah; Mohammad Hossein Karimi; Seyed Mohammad Moazzeni

Volume 14, Issue 4 , Autumn 2017, Pages 270-280

  Background: Type-1 diabetes (T1D) is an autoimmune disease in which T lymphocytes destroy insulin-producing β-cells. Control of self-reactive T lymphocytes and recovery of diabetic injury is the end point of T1D. Objective: To investigate generation of tolerogenic dendritic cells (tolDCs) as an ...  Read More

Original Article
3. Expression of Human Cytokine Genes Associated with Chronic Hepatitis B Disease Progression
Volume 14, Issue 4 , Autumn 2017, Pages 281-292

  Background: Hepatitis viruses are non-cytopathic viruses that lead to the infection and pathogenesis of liver diseases as a result of immunologically mediated event. Objective: To investigate the expression of human inflammatory cytokines in chronic hepatitis B patients according to the severity of the ...  Read More

Original Article
4. Cytokine Profile of Leishmania Infantum Fucose-Mannose Ligand in Vaccinated Dogs in the Northwest of Iran

Behnam Mohammadi-Ghalehbin; Gholamreza Hatam; Bahador Sarkari; Mehdi Mohebali; Zabih Zarei; Shahab Bohlooli

Volume 14, Issue 4 , Autumn 2017, Pages 293-305

  Background: Canine visceral leishmaniasis (CVL) caused by Leishmania infantum is endemic in the northwest and south of Iran. An appropriate vaccine can help to prevent and control visceral leishmaniasis in both humans and animals. Few studies have confirmed that the fucose-mannose ligand (FML) antigen ...  Read More

Original Article
5. The Reaction of Placental GRP78 Protein with Sera from Women with Multiple Sclerosis

Behrouz Gharesi-Fard; Maryam Zare; Eskandar Kamali-Sarvestani

Volume 14, Issue 4 , Autumn 2017, Pages 306-315

    Background: Multiple Sclerosis (MS) with four different types is one of the well studied autoimmune diseases of the central nervous system. Generally, two-thirds of MS patients are females who are at risk of pregnancy-related complications. Inappropriate responses of mother’s immune system, ...  Read More

Original Article
6. Evaluation of the miRNA-146a and miRNA-155 Expression Levels in Patients with Oral Lichen Planus

Fatemeh Ahmadi-Motamayel; Zeynab Bayat; Mehrdad Hajilooi; Soroosh Shahryar-Hesami; Ali Mahdavinezhad; Lida Samie; Ghasem Solgi

Volume 14, Issue 4 , Autumn 2017, Pages 316-324

  Background: Oral Lichen Planus (OLP) is a chronic autoimmune disease that could be considered as a potential premalignant status. Objective: To evaluate the miRNA-146a and miRNA-155 expression levels in patients with oral Lichen planus lesions compared to healthy subjects with normal oral mucosa. Methods: ...  Read More

Original Article
7. Non-Viable Lactobacillus Casei Beneficially Modulates Poly I:C Immune Response in Co-Cultures of Human Cells

Elisa Vintiñi; Marcela Medina

Volume 14, Issue 4 , Autumn 2017, Pages 325-339

    Background: Polyinosinic:polycytidylic acid (Poly-IC) has been used as a viral stimulus to mimic in vivo and in vitro infection induced by some viruses. Objective: To determine whether non-viable Lactobacillus casei CRL431 (LcM) can modulate the immune response induced by Poly I:C in co-culture ...  Read More

Short Paper
8. IL-6/IL-10 Ratio as A Prognostic and Predictive Marker of the Severity of Inherited Epidermolysis Bullosa

Marilina Tampoia; Letizia Abbracciavento; Marella Morrone; Ruggiero Fumarulo

Volume 14, Issue 4 , Autumn 2017, Pages 340-349

  Background: Recent studies have shown that cytokines have an important role in the pathogenesis of inflammatory diseases and can be used as prognostic markers. Objective: To evaluate the IL-6/IL-10 ratio in patients with Inherited Epidermolysis Bullosa (EB) as a prognostic marker. Methods: Serum levels ...  Read More