Volume 18 (2021)
Volume 17 (2020)
Volume 16 (2019)
Volume 14 (2017)
Volume 13 (2016)
Volume 12 (2015)
Volume 11 (2014)
Volume 10 (2013)
Volume 9 (2012)
Volume 8 (2011)
Volume 7 (2010)
Volume 6 (2009)
Volume 5 (2008)
Volume 4 (2007)
Volume 3 (2006)
Volume 2 (2005)
Volume 1 (2004)
Review Article
1. Role of Interleukin-37 in Inflammatory and Autoimmune Diseases

Xiaoying Wang; Keye Xu; Sisi Chen; Yan Li; Mingcai Li

Volume 15, Issue 3 , Summer 2018, Pages 165-174


  Interleukin-1 family 7 (IL-1F7) is a novel member of IL-1F cytokines. IL-1F7 is more commonly known as IL-37. IL-37 join the α-subunit of the IL-18 receptor, or IL-18 binding protein (IL-18BP), and binding of these proteins can enhance the IL-18 suppression. IL-37 also translocates to the cell ...  Read More

Original Article
2. T Helper Cells Profile and CD4+CD25+Foxp3+Regulatory T Cells in Polycystic Ovary Syndrome

Fatemeh Nasri; Mehrnoosh Doroudchi; Bahia Namavar Jahromi; Behrouz Gharesi-Fard

Volume 15, Issue 3 , Summer 2018, Pages 175-185


  Background: Polycystic ovary syndrome (PCOS) is considered as the most common cause of female infertility that affects 4-10% of women in the reproductive age. Previous studies have shown the role of a balanced immune response in a successful pregnancy and fertility. Objective: To investigate the T helper ...  Read More

Original Article
3. Vitamin D3 Induced Decrease in IL-17 and Malondialdehyde, and Increase in IL-10 and Total Antioxidant Capacity Levels in Patients with Irritable Bowel Syndrome

Reza Amani; Amir Abbasnezhad; Eskandar Hajiani; Bahman Cheraghian; Zahra Abdoli; Razieh Choghakhori

Volume 15, Issue 3 , Summer 2018, Pages 186-196


  Background: Given the variations in clinical presentation and physiopathological mechanisms in irritable bowel syndrome (IBS) subtypes, it is an acknowledged fact that the response to treatments can be disparate. Objective: To assess the effect of vitamin D on inflammatory cytokines (IL-17, IL-10, TNF-α), ...  Read More

Original Article
4. Lower Frequency of HLA-DRB1*01 in Southwestern Iranian Patients with Atherosclerosis

Hossein Golmoghaddam; Shirin Farjadian; Shahdad Khosropanah; Pooyan Dehghani; Mehrnoosh Doroudchi

Volume 15, Issue 3 , Summer 2018, Pages 197-206


  Background: Human leukocyte antigen (HLA) complex is a gene family involved in antigen presentation associated with protection or susceptibility to inflammatory, infectious and autoimmune diseases. Atherosclerosis is a chronic inflammatory disease in which HLA molecules play a role in the initiation ...  Read More

Original Article
5. Designing and Expression of Recombinant Chimeric Protein Containing CtxB and OmpW from Vibrio Cholerae and Evaluation of Its Immunogenicity

Atina Vakili; Seyed Latif Mousavi Gargari; Shahram Nazarian; Jafar Amani

Volume 15, Issue 3 , Summer 2018, Pages 207-220


  Background: Cholera disease caused by Vibrio cholerae remains a major cause of morbidity and mortality throughout the world. Various strategies with different proteins as immunogens have been tried for vaccine development, none of which have been sufficiently effective to preclude cholera. Chimeric proteins, ...  Read More

Original Article
6. Circulating Levels of Interleukin-10 and -17 in Patients with Cerebral Sinovenous Thrombosis (CSVT) in Acute and Subacute Stages: A Prospective Case-Control Study

Sadegh Izadi; Afshin Borhani-Haghighi; Kamal Bastani; Bahareh Kardeh; Golnaz Yadollahi-Khales; Mojtaba Neydavoodi

Volume 15, Issue 3 , Summer 2018, Pages 221-227


  Background: Cerebral sinovenous thrombosis (CSVT) is a neurovascular disorder that occurs when a blood clot develops in a vein near the brain. Evaluating the subsequent changes in inflammatory cytokines can better reveal the underlying pathogeneses. Objective: To assess the serum levels of interleukin-10 ...  Read More

Original Article
7. The Soluble and Particulate Form of Alginates Positively Regulate Immune Response

Fei Ge; Longbao Zhu; Liangjun Yang; Wanzhen Li; Shenghua Wei; Yugui Tao; Guocheng Du

Volume 15, Issue 3 , Summer 2018, Pages 228-238


  Background: Alginate materials have been widely employed for biomedical applications ranging from wound healing to cancer treatment. However, how alginate materials affect the immune system is largely unknown. Objective: To explore the impact of alginate materials on immune system. Methods: The effect ...  Read More

Short Paper
8. Soluble CD163 Levels and CD163+CD14+ Monocyte/Macrophage Counts in Patients with Asthma

Yue Zhi; Peng Gao; Wei Li; Jie Zhang; Fengling Gao; Jichun Zhang; Haitao Lin

Volume 15, Issue 3 , Summer 2018, Pages 239-245


  Background: CD163-expressing macrophages are involved in the inflammatory response in asthma. Objective: To assess sputum and serum soluble CD163 (sCD163) and cytokine levels in patients with asthma. Further discussed was the difference between sCD163 and other classic inflammatory mediators. Methods: ...  Read More