Volume 18 (2021)
Volume 17 (2020)
Volume 16 (2019)
Volume 15 (2018)
Volume 14 (2017)
Volume 13 (2016)
Volume 12 (2015)
Volume 11 (2014)
Volume 10 (2013)
Volume 9 (2012)
Volume 8 (2011)
Volume 7 (2010)
Volume 6 (2009)
Volume 5 (2008)
Volume 3 (2006)
Volume 2 (2005)
Volume 1 (2004)
Review Article
1. Killer Cell Immunoglobulin-Like Receptors Influence the Innate and Adaptive Immune Responses

Raja Rajalingam

Volume 4, Issue 2 , Spring 2007, Pages 61-78

  Natural killer (NK) cells are a subset of lymphocytes which play a crucial role in early innate immune response against infection and tumor transformation. Furthermore, they secrete interferon-γ (IFN-γ) and tumor necrosis factor (TNF) prompting adaptive immu-nity. NK cells distinguish the ...  Read More

Original Article
2. Positional Relationship between Natural Killer Cells and Distribution of Sympathetic Nerves in Decidualized Mouse Uterus

Abdolkarim Sheikhi; Hossein B. Ganji; Razieh Sheikhi

Volume 4, Issue 2 , Spring 2007, Pages 79-84

  Background: Uterine natural killer (uNK) cells are the most abundant leukocytes in pre-implantation endometrium and early pregnancy deciduas in humans and rodents. They are associated with structural changes in maternal spiral arteries but regulation of their re-cruitment and activation is incompletely ...  Read More

Original Article
3. HLA class II Genetic Diversity in Arabs and Jews of Iran

Shirin Farjadian; Abbas Ghaderi

Volume 4, Issue 2 , Spring 2007, Pages 85-93

  Background: Anthropological studies based on highly polymorphic HLA genes pro-vide useful information for bone marrow donor registry, forensic medicine, disease as-sociation studies, as well as designing peptide vaccines against tumors, and infectious or autoimmune diseases. Objective: This study was ...  Read More

Original Article
4. Association between HLA-DRB1*01 and HLA-Cw*08 and Outcome Following HTLV-I Infection

Houshang Rafatpanah; Vera Pravica; Reza FaridHosseini; Abbas Tabatabaei; Wiliam Ollier; Kay Poulton; Wendy Thomson; Ian Hutchinson

Volume 4, Issue 2 , Spring 2007, Pages 94-100

  Background: Human T cell lymphotropic virus type I (HTLV-I)-associated myelopa-thy/tropical spastic paraparesis (HAM/TSP) is an inflammatory disease which occurs in less than 2% of HTLV-I -infected individuals. High proviral load, high HTLV-I-specific CD8+ cytotoxic T lymphocyte frequency (CTL) and host ...  Read More

Original Article
5. Immunogenicity of a Triple Diphtheria-Tetanus-Whole Cell Pertussis Vaccine in Iranian Preschool Children

Saeed Zarei; Mahmood Jeddi-Tehrani; Mohammad Mehdi Akhondi; Hojjat Zeraati; Tahere Kheirkhah; Morteza Ghazanfari; Fazel Shokri

Volume 4, Issue 2 , Spring 2007, Pages 101-109

  Background: Immunization against diphtheria, tetanus and pertussis has been applied in Iran since 1950. WHO suggests periodical evaluation of effectiveness of the triple diphtheria-tetanus-whole cell pertussis (DTwP) vaccine, worldwide. Objectives: To determine the immunogenicity of locally manufactured ...  Read More

Original Article
6. Sex Hormones and Peripheral White Blood Cell Subsets in Systemic Lupus Erythematosus Patients

Maryam Rastin; Mohammad Reza Hatef; Nafise Tabasi; Akram Sheikh; Javid Morad Abbasi; Mahmoud Mahmoudi

Volume 4, Issue 2 , Spring 2007, Pages 110-115

  Background: Systemic Lupus Eyrythematosus (SLE) is an autoimmune disease charac-terized by antibodies to nuclear antigens, particularly anti-dsDNA. Imbalance between production and destruction of immune cells causes cytopenia. Sex hormones have im-munomodulatory effects; estrogen increases the production ...  Read More

Original Article
7. Comparison of Serological Methods (ELISA, DAT and IFA) for Diagnosis of Visceral Leishmaniasis Utilizing an Endemic Strain

Fattaneh Mikaeili; Mahdi Fakhar; Bahador Sarkari; Mohammad H. Motazedian; Gholamreza Hatam

Volume 4, Issue 2 , Spring 2007, Pages 116-121

  Background: The causative agent of visceral leishmaniasis (VL) in Iran is Leishmania infantum (L. infantum) (Mediterranean type) and its major reservoir host is the dog. Ob-jective: To compare the serological methods including direct agglutination test (DAT), indirect immunofluorescent-antibody test ...  Read More

Case Report
8. Perforin Gene Analaysis in an Iranian Family with Familial Hemophagocytic Lymphohistiocytosis

Hamid Galehdari; Ebrahim Mohammadi; Behnaz Andashti; Ali Naderi; Mohammad Ali Molavi

Volume 4, Issue 2 , Spring 2007, Pages 122-126

  Perforin gene (PRF1) mutations have been reported in 20-30% of patients with familial hemophagocytic lymphohistiocytosis (FHL), an immune disorder of infancy and early childhood. Cytotoxic T and natural killer (NK) cell activities are remarkably reduced or ab-sent in FHL patients. We report the first ...  Read More