Volume 21 (2024)
Volume 20 (2023)
Volume 19 (2022)
Volume 18 (2021)
Volume 17 (2020)
Volume 16 (2019)
Volume 15 (2018)
Volume 14 (2017)
Volume 13 (2016)
Volume 12 (2015)
Volume 11 (2014)
Volume 10 (2013)
Volume 9 (2012)
Volume 8 (2011)
Volume 7 (2010)
Volume 6 (2009)
Volume 5 (2008)
Volume 3 (2006)
Volume 2 (2005)
Volume 1 (2004)
Review Article
Killer Cell Immunoglobulin-Like Receptors Influence the Innate and Adaptive Immune Responses

Raja Rajalingam

Volume 4, Issue 2 , June 2007, Pages 61-78

Abstract
  Natural killer (NK) cells are a subset of lymphocytes which play a crucial role in early innate immune response against infection and tumor transformation. Furthermore, they secrete interferon-γ (IFN-γ) and tumor necrosis factor (TNF) prompting adaptive immu-nity. NK cells distinguish the ...  Read More

Original Article
Positional Relationship between Natural Killer Cells and Distribution of Sympathetic Nerves in Decidualized Mouse Uterus

Abdolkarim Sheikhi; Hossein B. Ganji; Razieh Sheikhi

Volume 4, Issue 2 , June 2007, Pages 79-84

Abstract
  Background: Uterine natural killer (uNK) cells are the most abundant leukocytes in pre-implantation endometrium and early pregnancy deciduas in humans and rodents. They are associated with structural changes in maternal spiral arteries but regulation of their re-cruitment and activation is incompletely ...  Read More

Original Article
HLA class II Genetic Diversity in Arabs and Jews of Iran

Shirin Farjadian; Abbas Ghaderi

Volume 4, Issue 2 , June 2007, Pages 85-93

Abstract
  Background: Anthropological studies based on highly polymorphic HLA genes pro-vide useful information for bone marrow donor registry, forensic medicine, disease as-sociation studies, as well as designing peptide vaccines against tumors, and infectious or autoimmune diseases. Objective: This study was ...  Read More

Original Article
Association between HLA-DRB1*01 and HLA-Cw*08 and Outcome Following HTLV-I Infection

Houshang Rafatpanah; Vera Pravica; Reza FaridHosseini; Abbas Tabatabaei; Wiliam Ollier; Kay Poulton; Wendy Thomson; Ian Hutchinson

Volume 4, Issue 2 , June 2007, Pages 94-100

Abstract
  Background: Human T cell lymphotropic virus type I (HTLV-I)-associated myelopa-thy/tropical spastic paraparesis (HAM/TSP) is an inflammatory disease which occurs in less than 2% of HTLV-I -infected individuals. High proviral load, high HTLV-I-specific CD8+ cytotoxic T lymphocyte frequency (CTL) and host ...  Read More

Original Article
Immunogenicity of a Triple Diphtheria-Tetanus-Whole Cell Pertussis Vaccine in Iranian Preschool Children

Saeed Zarei; Mahmood Jeddi-Tehrani; Mohammad Mehdi Akhondi; Hojjat Zeraati; Tahere Kheirkhah; Morteza Ghazanfari; Fazel Shokri

Volume 4, Issue 2 , June 2007, Pages 101-109

Abstract
  Background: Immunization against diphtheria, tetanus and pertussis has been applied in Iran since 1950. WHO suggests periodical evaluation of effectiveness of the triple diphtheria-tetanus-whole cell pertussis (DTwP) vaccine, worldwide. Objectives: To determine the immunogenicity of locally manufactured ...  Read More

Original Article
Sex Hormones and Peripheral White Blood Cell Subsets in Systemic Lupus Erythematosus Patients

Maryam Rastin; Mohammad Reza Hatef; Nafise Tabasi; Akram Sheikh; Javid Morad Abbasi; Mahmoud Mahmoudi

Volume 4, Issue 2 , June 2007, Pages 110-115

Abstract
  Background: Systemic Lupus Eyrythematosus (SLE) is an autoimmune disease charac-terized by antibodies to nuclear antigens, particularly anti-dsDNA. Imbalance between production and destruction of immune cells causes cytopenia. Sex hormones have im-munomodulatory effects; estrogen increases the production ...  Read More

Original Article
Comparison of Serological Methods (ELISA, DAT and IFA) for Diagnosis of Visceral Leishmaniasis Utilizing an Endemic Strain

Fattaneh Mikaeili; Mahdi Fakhar; Bahador Sarkari; Mohammad H. Motazedian; Gholamreza Hatam

Volume 4, Issue 2 , June 2007, Pages 116-121

Abstract
  Background: The causative agent of visceral leishmaniasis (VL) in Iran is Leishmania infantum (L. infantum) (Mediterranean type) and its major reservoir host is the dog. Ob-jective: To compare the serological methods including direct agglutination test (DAT), indirect immunofluorescent-antibody test ...  Read More

Case Report
Perforin Gene Analaysis in an Iranian Family with Familial Hemophagocytic Lymphohistiocytosis

Hamid Galehdari; Ebrahim Mohammadi; Behnaz Andashti; Ali Naderi; Mohammad Ali Molavi

Volume 4, Issue 2 , June 2007, Pages 122-126

Abstract
  Perforin gene (PRF1) mutations have been reported in 20-30% of patients with familial hemophagocytic lymphohistiocytosis (FHL), an immune disorder of infancy and early childhood. Cytotoxic T and natural killer (NK) cell activities are remarkably reduced or ab-sent in FHL patients. We report the first ...  Read More