Volume 18 (2021)
Volume 17 (2020)
Volume 16 (2019)
Volume 15 (2018)
Volume 14 (2017)
Volume 13 (2016)
Volume 12 (2015)
Volume 10 (2013)
Volume 9 (2012)
Volume 8 (2011)
Volume 7 (2010)
Volume 6 (2009)
Volume 5 (2008)
Volume 4 (2007)
Volume 3 (2006)
Volume 2 (2005)
Volume 1 (2004)
Original Article
1. Islet Amyloid Polypeptide is not a Target Antigen for CD8+ T-Cells in Type 2 Diabetes

Fathollah Kalantar; Mohammad Hossein Dabbaghmanesh; Emanuela Martinuzzi; Mohsen Moghadami; Zahra Amirghofran

Volume 11, Issue 1 , Winter 2014, Pages 1-12

  Background: Type 2 diabetes (T2D) is a chronic metabolic disorder in which beta-cells are destroyed. The islet amyloid polypeptide (IAPP) produced by beta-cells has been reported to influence beta-cell destruction. Objective: To evaluate if IAPP can act as an autoantigen and therefore, to see if CD8 ...  Read More

Original Article
2. The Effect of HLA-DRB1 Sharing between the Couples with Recurrent Pregnancy Loss on the Pregnancy Outcome after Leukocyte Therapy

Behrouz Gharesi-Fard; Rahil Askarinejad-Behbahani; Shabnam Behdin

Volume 11, Issue 1 , Winter 2014, Pages 13-20

  Background: Miscarriage is a common phenomenon complicating more than half of pregnancies. Recurrent Pregnancy Loss (RPL) is defined as three or more pregnancies lost before the twentieth week of gestation. It is believed that abnormality in maternal immune reaction to fetus and sharing of HLA antigens ...  Read More

Original Article
3. Association of HLA-Class II and IgE Serum Levels in Pediatric Asthma

Mahendra Narain Mishra; Puja Dudeja; Rakesh Kumar Gupta

Volume 11, Issue 1 , Winter 2014, Pages 21-28

  Background: Pediatric bronchial asthma is associated with considerable morbidity. The study was carried out to examine the association of Human Leukocyte Antigen (HLA)- Class II with the disease as we found no similar study on Asian Indian population. Objective: To define the HLA-Class II antigens in ...  Read More

Original Article
4. Interleukin-17 Gene Expression and Serum Levels in Acute Rejected and non-Rejected Liver Transplant Patients

Afsoon Afshari; Ramin Yaghobi; Mohammad Hossein Karimi; Mojtaba Darbooie; Negar Azarpira

Volume 11, Issue 1 , Winter 2014, Pages 29-39

  Background: Interleukin-17 (IL-17), as a potent proinflammatory cytokine, has a critical role in post liver transplant outcomes. However, there is not much information about the effects of IL-17 cytokine on acute liver rejection. Objective: To evaluate the role of IL-17 in post-liver transplant acute ...  Read More

Original Article
5. Negative Association of Serum IL-6 and IL-17 with Type-II Diabetes Retinopathy

Nadeem Afzal; Shakeela Zaman; Aneela Asghar; Khursheed Javed; Faheem Shahzad; Abu Zafar; Abdul Hanan Nagi

Volume 11, Issue 1 , Winter 2014, Pages 40-48

  Background: Diabetes mellitus (DM) is a health concern which leads to complications such as retinopathy. Pakistan has 6.9 million people living with DM and this toll will be doubled by 2025. Objective: To determine serum IL-6 and IL-17 of type 2 diabetes mellitus (T2DM) patients with retinopathy. Methods: ...  Read More

Original Article
6. Primary Antibody Deficiencies at Queen Rania Children Hospital in Jordan: Single Center Experience

Zeyad M.Habahbeh; Mohammad E Abu-Shukair; Mohammad A. Almutereen; Raed M. Alzyoud; Adel M Wahadneh

Volume 11, Issue 1 , Winter 2014, Pages 49-58

  Background: Primary antibody deficiency, the most common primary immunodeficiency disorder, represents a heterogeneous spectrum of conditions caused by a defect in any critical stage of B cell development and is characterized by impaired production of normal amounts of antigen-specific antibodies. Objective: ...  Read More

Case Report
7. A Case of Bruton’s Disease with Normal Immunoglobulin G Level

Soheila Alyasin; Farhad Abolnezhadian; Amir Rezaei

Volume 11, Issue 1 , Winter 2014, Pages 59-63

  X-linked agamaglobulinemia (XLA) or Bruton’s disease is a genetic disease resulting from a mutation in the Bruton’s tyrosine kinase (Btk) gene. This mutation leads to B cell arrest during differentiation (1). This disease was first described by Ogden Bruton in 1952 (2). Approximately 85% ...  Read More