Volume 18 (2021)
Volume 17 (2020)
Volume 16 (2019)
Volume 15 (2018)
Volume 14 (2017)
Volume 13 (2016)
Volume 12 (2015)
Volume 10 (2013)
Volume 9 (2012)
Volume 8 (2011)
Volume 7 (2010)
Volume 6 (2009)
Volume 5 (2008)
Volume 4 (2007)
Volume 3 (2006)
Volume 2 (2005)
Volume 1 (2004)
Original Article
1. CTL Responses to DCs Stimulated with Leishmania Antigens Detected by DCs Expressing Leishmania gp63

Hossein Rezvan; Ali Khodadadi; Selman Ali

Volume 11, Issue 2 , Spring 2014, Pages 65-73

  Background: Leishmania is a pathogenic parasite which infects mononuclear cells in vertebrate hosts. Different strategies have been taken to develop immunity against Leishmania . DCs loaded with immunogenic antigen have resulted in different levels of Th1-type immune response and cytotoxic T lymphocytes ...  Read More

Original Article
2. Toll Like Receptor 2 and 4 Expression in Peripheral Blood Mononuclear Cells of Multiple Sclerosis Patients

Seyed Javad Hasheminia; Sayyed Hamid Zarkesh-Esfahani; Sepideh Tolouei; Vahid Shaygannejad; Hedaiatallah Shirzad; Morteza Hashemzadeh Chaleshtory

Volume 11, Issue 2 , Spring 2014, Pages 74-83

  Background: Multiple sclerosis (MS) is a T cell mediated autoimmune disease with unknown etiology. Appropriate MS therapeutic strategies need thorough understanding of both disease etiology and pathogenesis mechanisms. Ligation of TLR-2 and TLR-4 stimulates the production of several cytokines leading ...  Read More

Original Article
3. Increase of CD69, CD161 and CD94 on NK Cells in Women with Recurrent Spontaneous Abortion and in Vitro Fertilization Failure

Mehri Ghafourian; Najmeh Karami; Ali Khodadadi; Roshan Nikbakhat

Volume 11, Issue 2 , Spring 2014, Pages 84-96

  Background: Recurrent spontaneous abortion (RSA) and in vitro fertilization (IVF) failure with unknown causes are the controversial issues that are probably related to the immune system. Objective: To compare circulating NK cells expressing activation and inhibition surface markers between patients with ...  Read More

Original Article
4. IL-6, IL-10 and IL-17 Gene Polymorphisms in Iranian Women with Recurrent Miscarriage

Motahareh Bahadori; Saeed Zarei; Amir Hassan Zarnani; Omid Zarei; Farah Idali; Reza Hadavi; Mahmood Jeddi-Tehrani

Volume 11, Issue 2 , Spring 2014, Pages 97-104

  Background: Pro-inflammatory and anti-inflammatory cytokines and polymorphisms of their genes have been described to be involved in the pathogenesis of recurrent miscarriage (RM). Objective: To investigate the association between RM and five polymorphisms of cytokine genes, interleukin 10 (IL-10), (-592 ...  Read More

Original Article
5. FoxP3+ Regulatory T Cells in Peripheral Blood of Patients with Epithelial Ovarian Cancer

Nasrollah Erfani; Mahboobeh Hamedi-Shahraki; Somayeh Rezaeifard; Mohammadreza Haghshenas; Manoochehr Rasouli; Alamtaj Samsami Dehaghani

Volume 11, Issue 2 , Spring 2014, Pages 105-112

  Background: Ovarian cancer is the fifth leading cause of death from malignancy in women. CD4 +CD25+FoxP3+ regulatory T (Treg) cells are a subset of T lymphocytes with great inhibitory impact on immune response. Objectives: To investigate the percentage of CD4 +CD25+FoxP3+ regulatory T cells in the peripheral ...  Read More

Original Article
6. Propylene-Glycol Aggravates LPS-Induced Sepsis through Production of TNF-α and IL-6

Annamaria Marton; Csongor Kolozsi; Erzsebet Kusz; Zoltan Olah; Tamas Letoha; Csaba Vizler; Laszlo Pecze

Volume 11, Issue 2 , Spring 2014, Pages 113-122

  Background : Propylene glycol (1,2-propanediol, PG) is a commonly used solvent for oral, intravenous, as well as topical pharmaceutical preparations. While PG is generally considered to be safe, it has been known that large intravenous doses given over a short period of time can be toxic. Objective: ...  Read More

Original Article
7. Morbidity and Mortality of Iranian Patients with Hyper IgM Syndrome: a Clinical Analysis

Hassan Abolhassani; Fatemeh Akbari; Babak Mirminachi; Saeed Bazregari; Ehsan Hedayat; Nima Rezaei; Asghar Aghamohammadi

Volume 11, Issue 2 , Spring 2014, Pages 123-133

  Background: Defects in B cell class switch recombination (CSR) are a heterogeneous and yet very uncommon group of disorders which all have a genetic basis uniformly leading to hyper IgM (HIgM) syndrome. Due to the rare frequency of these conditions, a very small number of case series have been conducted ...  Read More

Short Paper
8. Correlation of Midkine Serum Level with Pro- and Anti-Inflamatory Cytokines in Multiple Sclerosis

Vahid Shaygannejad; Saeed Montazeri; Azam Jamshidian; Soheil Tahani; Marjan Gharagozloo; Fereshteh Ashtari; Sahar Vesal; Seyed Javad Hasheminia; Leila Dehghani

Volume 11, Issue 2 , Spring 2014, Pages 134-138

  Background: Midkine (MK) is a heparin-binding growth factor with promoting effects in inflammatory responses through enhancing leukocytes migration. Objective: To study the correlation between MK serum levels and concentration of inflammatory cytokines in Multiple Sclerosis (MS) patients. Methods: We ...  Read More