Volume 17 (2020)
Volume 15 (2018)
Volume 14 (2017)
Volume 13 (2016)
Volume 12 (2015)
Volume 11 (2014)
Volume 10 (2013)
Volume 9 (2012)
Volume 8 (2011)
Volume 7 (2010)
Volume 6 (2009)
Volume 5 (2008)
Volume 4 (2007)
Volume 3 (2006)
Volume 2 (2005)
Volume 1 (2004)
Review Article
1. Pathogenesis of Atopic Dermatitis: Current Paradigm

Masutaka Furue; Dugarmaa Ulzii; Yen Vu; Gaku Tsuji; Makiko Kido-Nakahara; Takeshi Nakahara

Volume 16, Issue 2 , Spring 2019, Pages 97-107

http://dx.doi.org/10.22034/iji.2019.80253

Abstract
  Atopic dermatitis (AD) is characterized by skin inflammation, barrier dysfunction and chronic pruritus. In this review, recent advances in the pathogenesis of AD are summarized. Clinical efficacy of the anti-IL-4 receptor antibody dupilumab implies that type 2 cytokines IL-4 and IL-13 have pivotal roles ...  Read More

Original Article
2. Correlation of 4-1BBL+ B Cells in Tumor Draining Lymph Nodes with Pathological Characteristics of Breast Cancer

Mohsen Arabpour; Atri Ghods; Mahmoud Shariat; Abodl-Rasoul Talei; Fereshteh Mehdipour; Abbas Ghaderi

Volume 16, Issue 2 , Spring 2019, Pages 108-116

http://dx.doi.org/10.22034/iji.2019.80254

Abstract
  Background: B cells can increase the expression of granzyme B in CD8+ T cells through 4-1BBL/4-1BB interaction and promote anti-tumor immunity. Objective: To investigate the expression of 4-1BBL on B cells in the breast tumor draining lymph nodes (TDLNs) and its association with disease parameters. Methods: ...  Read More

Original Article
3. Cell Density Counts of the Intestinal Intraepithelial Lymphocytes in the Celiac Patients

Hadi Hossein-Nataj; Mohsen Masjedi; Mohammad Hassan Emami; Mojgan Mokhtari; Fereshteh Alsahebfosoul

Volume 16, Issue 2 , Spring 2019, Pages 117-126

http://dx.doi.org/10.22034/iji.2019.80255

Abstract
  Background: Increased number of intestinal intraepithelial lymphocytes (IELs) is a key histological finding in the diagnosis of celiac disease (CD); however, the number of IELs in celiac patients and healthy subjects may vary from one region to another. Additionally, there are some seronegative celiac ...  Read More

Original Article
4. GPI-Anchored Fibromodulin as a Novel Target in Chronic Lymphocytic Leukemia: Diagnostic and Therapeutic Implications

Lia Farahi; Fatemeh Ghaemimanesh; Saeideh Milani; Seyed Mohsen Razavi; Reza Hadavi; Ali Ahmad Bayat; Ali Salimi; Mohammad Mehdi Akhondi; Hodjattallah Rabbani

Volume 16, Issue 2 , Spring 2019, Pages 127-141

http://dx.doi.org/10.22034/iji.2019.80256

Abstract
  Background: We have previously reported the aberrant expression of Fibromodulin (FMOD) in patients with chronic lymphocytic leukemia (CLL). Although FMOD has been considered as a cytoplasmic or secretory protein, we discovered the cell surface expression of FMOD in leukemic B cells via anchoring with ...  Read More

Original Article
5. CD93 is Selectively Expressed on Human Myeloma Cells but Not on B Lymphocytes

Shohreh Fakhari; Hamed Bashiri; Bayazid Ghaderi; Kaveh Tari; Ali Jalili

Volume 16, Issue 2 , Spring 2019, Pages 142-150

http://dx.doi.org/10.22034/iji.2019.80257

Abstract
  Background: CD93 has originally been known as a C1q receptor, and many studies have demonstrated that CD93 is expressed on hematopoietic stem cells, B cell progenitors, myeloid and monocytic cells. Moreover, CD93 is shown to be expressed on long-lived plasma cells, and CD93 deficient-mice display an ...  Read More

Original Article
6. Serum and Peritoneal Fluid Cytokine Profiles in Infertile Women with Endometriosis

Majid Tarokh; Marefat Ghaffari Novin; Tahereh Poordast; Zohreh Tavana; Hamid Nazarian; Mohsen Norouzian; Behrouz Gharesi-Fard

Volume 16, Issue 2 , Spring 2019, Pages 151-162

http://dx.doi.org/10.22034/iji.2019.80258

Abstract
  Background: Endometriosis is a chronic inflammatory disease with the growth of endometrial cells out of uterus and in the peritoneal cavity. T cell subsets participate in the establishment and progress of the disease by producing different cytokines. Objective: To investigate a group of cytokines related ...  Read More

Original Article
7. Evaluation of Exhausted Regulatory T Cells in Preeclampsia

Nahid Daraei; Mehri Ghafourian; Ata Ghadiri; Afshin Amari; Mahin Najafian; Saber Rokhafrooz

Volume 16, Issue 2 , Spring 2019, Pages 163-169

http://dx.doi.org/10.22034/iji.2019.80259

Abstract
  Background: The development of a maternal immune response to fetal antigens and deficiency in regulatory T-cells (Tregs) may lead to preeclampsia. A plausible explanation for the reduced Treg cell function in women with preeclampsia is the presence of exhausted Treg cells which express CD279 or programmed ...  Read More

Original Article
8. Reno-Protective Effect of Realgar Nanoparticles on Lupus Nephritis of MRL/Lpr Mice through STAT1

Weidong Xu; Zheng Chen; Xiaodong Shen; Chiheng Pi

Volume 16, Issue 2 , Spring 2019, Pages 170-181

http://dx.doi.org/10.22034/iji.2019.80260

Abstract
  Background: Realgar, an arsenic tetrasulfide compound, is a highly recognized traditional Chinese medicinal prescription that has been widely used to treat various diseases such as inflammatory diseases. However, there are still some problems in the clinical treatment of Realgar, such as large oral dose ...  Read More

Original Article
9. Roles of Dermcidin, Salusin-α, Salusin-β and TNF-α in the Pathogenesis of Human Brucellosis

Ayşe Sağmak Tartar; Şafak Ozer Balın; Ayhan Akbulut; Meltem Yardım; Suleyman Aydın

Volume 16, Issue 2 , Spring 2019, Pages 182-189

http://dx.doi.org/10.22034/iji.2019.80261

Abstract
  Background:Brucella spp. are facultative intracellular pathogens that can cause chronic infections in many tissues and organs. Objectives: To investigate serum dermcidin, salusin-alpha, salusin-beta and TNF-alpha levels and their correlation with each other in patients with acute brucellosis. Methods: ...  Read More