Volume 18 (2021)
Volume 17 (2020)
Volume 15 (2018)
Volume 14 (2017)
Volume 13 (2016)
Volume 12 (2015)
Volume 11 (2014)
Volume 10 (2013)
Volume 9 (2012)
Volume 8 (2011)
Volume 7 (2010)
Volume 6 (2009)
Volume 5 (2008)
Volume 4 (2007)
Volume 3 (2006)
Volume 2 (2005)
Volume 1 (2004)
Original Article
1. Hepcidin Induces M1 Macrophage Polarization in Monocytes or THP-1 Derived Macrophages

Enna Liu; Zheng Li; Yan Zhang; Kuisheng Chen

Volume 16, Issue 3 , Summer 2019, Pages 190-199


  Background: Macrophage polarization plays a critical role in determining the inflammatory states. Hepcidin is a key negative regulator of iron homeostasis and functions. Although hepcidin has been shown to affect ferroportin expression in macrophages, whether it affects macrophage polarization is still ...  Read More

Original Article
2. Immunogenic Evaluation of Bivalent Vaccine Candidate against Enterohemorrhagic and Enterotoxigenic Escherichia coli

Ahmad Karimi Rahjerdi; Mahyat Jafari; Mohammad Javad Motamedi; Jafar Amani; Ali Hatef Salmanian

Volume 16, Issue 3 , Summer 2019, Pages 200-211


  Background: Caused by bacterial, viral, and parasitic pathogens, diarrhea is the second leading cause of death among children under five. Two strains of E. coli, namely Enterotoxigenic, ETEC and Enterohemorrhagic EHEC are the most important causes of this disease in developing countries. EHEC is a major ...  Read More

Original Article
3. IpaD-loaded N-trimethyl Chitosan Nanoparticles Can Efficiently Protect Guinea Pigs against Shigella Flexneri

Mohammad Reza Akbari; Mojtaba Saadati; Hosein Honari; Hadi Mohammad Ghorbani

Volume 16, Issue 3 , Summer 2019, Pages 212-224


  Background: Shigella flexneri is a pathogen responsible for shigellosis around the world, especially in developing countries. Many immunogenic antigens have been introduced as candidate vaccines against Shigella, including N-terminal region of IpaD antigen (NIpaD). Objective: To evaluate the efficiency ...  Read More

Original Article
4. The Impact of Early Postpartum Maternal Pertussis Vaccination on the Protection of Infants: A Randomized Clinical Trial

Ayse Kilic; Gulcin Otar Yener; Aylin Yetim; Mustafa Ozcetin; Gulbin Gokcay; Asuman Coban; Zeynep Ince; Beril Yasa; Lutfiye Oksuz; Funda Gungor Ugurlucan; Nezahat Gurler

Volume 16, Issue 3 , Summer 2019, Pages 225-234


  Background: Despite primary vaccination, infants under six months run a risk of infection with pertussis. Objective: To determine the impact of early postpartum maternal pertussis vaccination on protecting infants from the disease. Methods: All mothers (n=405) who gave birth to healthy term infants were ...  Read More

Original Article
5. CEA Plasmid as Therapeutic DNA Vaccination against Colorectal Cancer

Ziba Veisi Malekshahi; Nasser Hashemi Goradel; Mehdi Shakouri Khomartash; Amir Maleksabet; Maryam kadkhodazadeh; Gholam Ali Kardar; Babak Negahdari

Volume 16, Issue 3 , Summer 2019, Pages 235-245


  Background: Human colorectal cancer cells overexpress carcinoembryonic antigen (CEA). CEA is a glycoprotein which has shown to be a promising vaccine target for immunotherapy against colorectal cancer. Objective: To design a DNA vaccine harboring CEA antigen and evaluate its effect on inducing immunity ...  Read More

Original Article
6. Effects of CD133 Silencing on Survival and Migration of HT-29 Colorectal Cancer Cells

Morteza Akbari; Dariush Shanehbandi; Milad Asadi; Navid Shomali; Afsaneh Faraji; Vahid Khaze; Abbas Pakdel; Ahad Mokhtarzadeh; Ali Asghar Ebrahimi; Aliakbar Shabani; Behzad Baradaran

Volume 16, Issue 3 , Summer 2019, Pages 246-257


  Background: Colorectal cancer (CRC) is attributed as one of the most common malignancies worldwide. CD133 molecule, as a pentaspan transmembrane glycoprotein, confers stem cell-related characteristics, including self-renewal and multi-directional differentiation capability. CD133 plays important roles ...  Read More

Original Article
7. IgG Avidity Test for Ocular Toxoplasmosis Diagnosis at a Tertiary Center, Northeast of Iran

Elham Moghaddas; Seyedeh Maryam Hosseini; Karim Sharifi; Abdolrahim Rezai; Saman Soleimanpour; Mohammad Mobin Miri Moghaddam; Seyed Aliakbar Shamsian

Volume 16, Issue 3 , Summer 2019, Pages 258-264


  Background: The diagnostic methods which are used for acute ocular toxoplasmosis are very important; if the treatment is delayed, it sometimes leads to loss of vision. Fewstudies have been performed to evaluate serological tests used in the diagnosis of acute ocular toxoplasmosis. Objective: To evaluate ...  Read More