Volume 18 (2021)
Volume 17 (2020)
Volume 15 (2018)
Volume 14 (2017)
Volume 13 (2016)
Volume 12 (2015)
Volume 11 (2014)
Volume 10 (2013)
Volume 9 (2012)
Volume 8 (2011)
Volume 7 (2010)
Volume 6 (2009)
Volume 5 (2008)
Volume 4 (2007)
Volume 3 (2006)
Volume 2 (2005)
Volume 1 (2004)
Original Article
1. Effects of Dendritic Cell Vaccine Activated with Components of Lieshmania Major on Tumor Specific Response

Samaneh Arab; Masoumeh Motamedi; Jamshid Hadjati

Volume 16, Issue 4 , Autumn 2019, Pages 268-277


  Background: Dendritic cells (DCs) contribute essentially to the outset and course of immune responses. So in patients with malignancy, there have been considerable interests in use of these cells in different interventions. Objective: To evaluate the impact of Leishmania major’s components ...  Read More

Original Article
2. Multiple Myeloma Bone Marrow Mesenchymal Stromal Cells Inhibit CD8+ T Cell Function in a Process that May Implicate Fibroblast Activation Protein α

Yadan Wang; Xiaofei Wu; Yu Hu

Volume 16, Issue 4 , Autumn 2019, Pages 278-290


  Background: Multiple myeloma (MM) is a malignant plasma cell proliferative disorder with limited immunotherapy treatment because of T cell dysfunction. Objective: To investigate the immunomodulatory function of bone marrow mesenchymal stromal cells (MM-BMSCs) on CD8+ T cells. Methods: Proliferation and ...  Read More

Original Article
3. NK, NKT and Invariant-NKT Cells in Tumor Draining Lymph Nodes of Patients with Breast Cancer

Somayeh Rezaeifard; Akbar Safaei; Abdolrasoul Talei; Zahra Faghih; Nasrollah Erfani

Volume 16, Issue 4 , Autumn 2019, Pages 291-298


  Background: NK (natural killer) and NKT (natural killer T) cells, as components of innate immune system, play a crucial role in tumor progression and dissemination. Objective: To investigate the percentages of NK cells, NKT cells, iNKT (invariant natural killer T) cells, total T lymphocytes as well as ...  Read More

Original Article
4. Decreased Level of IL-37 Correlates Negatively with Inflammatory Cytokines in Cerebrospinal Fluid of Patients with Neuro-Behcet’s Disease

Imene Ben Dhifallah; Afshin Borhani-Haghighi; Agnes Hamzaoui; Kamel Hamzaoui

Volume 16, Issue 4 , Autumn 2019, Pages 299-310


  Background: Behçet's disease (BD) is a systemic inflammatory disease with a chronic, relapsing-remitting course of unknown etiology. Neuro-Behcet’s disease (NBD) induce serious CNS complications and are known to be the main cause of long-term morbidity and mortality. IL‐37 is a natural ...  Read More

Original Article
5. Importance of L. Infantum H2B Recombinant Antigen for Serodiagnosis of Visceral Leishmaniasis

Zahra Rezaei; Gholamreza Pouladfar; Amin Ramezani; Zohreh Mostafavi-Pour; Amin Abbasian; Bahador Sarkari; Bahman Pourabbas

Volume 16, Issue 4 , Autumn 2019, Pages 311-320


  Background: Visceral leishmaniasis (VL) can lead to death in more than 95% of cases if left untreated. Accurate and early diagnosis has an important role in reducing mortality rate of this disease. Objective: To express recombinant H2B antigen from an Iranian isolate of Leishmania Infantum and evaluate ...  Read More

Short Paper
6. IL-25 and IL-33 Serum Levels are not Associated with the Type of Allergen Causing Allergic Rhinitis

Reza Abbasi; Kamiar Zomorodian; Zahra Zare Shahrabadi; Farshid Saadat; Seyed Hesamedin Nabavizadeh; Hossein Esmaeilzadeh; Sohila Alyasin

Volume 16, Issue 4 , Autumn 2019, Pages 321-326


  Background: Fungal aeroallergens might sensitize the airway which in turn produces a specific cytokine profile. Objective: To evaluate the IL-25 and IL-33 profile in patients with fungal allergic rhinitis. Methods: The present study examined patients who were evaluated due to allergic rhinitis (AR) at ...  Read More

Short Paper
7. Circulating Levels of Pro-inflammatory Cytokines in Patients with Nonalcoholic Fatty Liver Disease and Non-Alcoholic Steatohepatitis

Abolghasem Hadinia; Amir Hossein Doustimotlagh; Hamed Reza Goodarzi; Arash Arya; Mojtaba Jafarinia

Volume 16, Issue 4 , Autumn 2019, Pages 327-333


  Background: Pro-inflammatory cytokines are associated with systemic inflammatory responses. Objective: To investigate the levels of pro-inflammatory cytokines (IL-1b, IL-6, and TNF-a) in patients with non-alcoholic fatty liver (NAFL) and non-alcoholic steatohepatitis (NASH) compared to healthy individuals. ...  Read More

Case Report
8. Atypical Omenn Syndrome Due to RAG2 Gene Mutation, a Case Report

Ali Pourvali; Saba Arshi; Mohammad Nabavi; Mohammad Hasan Bemanian; Sima Shokri; Mohammad Shahrooei; Nima Rezaei; Morteza Fallahpour

Volume 16, Issue 4 , Autumn 2019, Pages 334-338


  Severe Combined Immunodeficiency (SCID), characterized by a profound decrease in both the number and function of T cells, is related to more than 20 different mutations. Recombination-activating gene (RAG) 1 and 2 seem to be two of the most common forms presenting with various manifestations, ...  Read More